Bone-Bonding Ability of Anodized Titanium Plate Loaded With Hydroxyapatite Particles

Abstract

Submicron-sized hydroxyapatite (HAp) particles were loaded on the titanium plate by anodic oxidation over spark discharge voltage in HAp-containing bath. The biocompatibility and bioactivity were drastically improved by HAp deposition on the anodic oxide films. The affinity with living bone was the following order: anodized titanium plate with HAp > anodized titanium plate >> titanium. Bone-bonding strength between HAp-loaded titanium plate and living bone after 4 weeks' implant was much higher than that of anodized titanium plate.

Surface Characteristics of Titanium Oxide Films Prepared by Micro-Arc Oxidation: Comparison of Direct Current Electrolysis and Pulse Electrolysis

“…[6][7][8][9] Of these techniques, micro-arc oxidation (MAO) has recently attracted considerable interest because newly formed titanium oxide films produced by MAO are highly porous and adhere firmly to titanium. [10][11][12][13] By controlling the composition and concentration of the electrolyte, Ca-and P-containing ceramics such as hydroxyapatite have been incorporated into the surface layer by us 14) and others. [15][16][17] There are two kinds of MAO techniques: those that employ direct current electrolysis 18,19) and those that use pulse electrolysis.…”

Fine Patterning of Titanium Oxide Film Loaded with Hydroxyapatite Using Photopatterning and Anodic Oxidation

“…7) Furthermore, it has been revealed by us and others that much smaller pores (1$2 mm) formed by anodic oxidation were also effective for bone conductivity. 8,9) As excellent surface modification, N. Noma et al reported the fine patterning by use of the photosensitive TiO 2 gel film. 10) In search for effective surface modification, we have already reported micrometer-scale patterning of micro-arc oxidized titanium film using photoirradiating in a preliminary form, 11) and have also demonstrated HAp-incorporation into the surface of TiO 2 oxide by anodic oxidation in HAp-containing electrolyte, which functions well to induce new bone formation.…”