Bone-like apatite coating on Mg-PSZ/Al2O3 composites using bioactive systems

Nogiwa, A. A.; Cortés, D. A.

doi:10.1007/s10856-006-0541-8

Cited by 9 publications

(4 citation statements)

References 17 publications

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“…3a) is demonstrated. According to the EDS analysis a compound with an atomic Ca/P ratio = 1.58-2.3 was obtained, which may correspond to octacalcium phosphate (OCP) [12]. As observed, the incorporation of pseudowollastonite particles promotes the growth of the bioactive layer.…”

Section: Resultsmentioning

confidence: 82%

Bioactive and Biocompatible Silica/Pseudowollastonite Aerogels

Reséndiz-Hernández

Cortés-Hernández

Nonell

et al. 2014

Advances in Science and Technology

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Silica aerogels have attracted increasingly more attention due to their extraordinary properties and their existing and potential applications in a wide variety of technological areas. Materials that promote bone-tissue formation at their surface and bond to osseous tissues when implanted are called bioactive, such as pseudowollastonite particles. In this work, the synthesis of aerogels with pseudowollastonite particles was performed. The synthesis involved the preparation of an alcogel by a two step sol-gel route followed by ambient pressure drying. To promote a higher bioactivity the obtained aerogels were then biomimetically treated using simulated body fluids, SBF and 1.5 SBF. A high bioactivity was demonstrated by FT-IR, SEM, EDS, and XRD. The in vitro biocompatibility was assessed by testing cytotoxicity using rat osteoblasts cultures. The results obtained indicate that these materials are highly potential aerogels for bone tissue regeneration.

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Section: Resultsmentioning

confidence: 82%

Bioactive and Biocompatible Silica/Pseudowollastonite Aerogels

Reséndiz-Hernández

Cortés-Hernández

Nonell

et al. 2014

Advances in Science and Technology

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“…The biomimetic methods consist mainly in the deposition of a bonelike apatite layer on the substrate by immersing samples in simulated body fluids (SBF, 1.4 SBF, 1.5 SBF and 5 SBF). As reported previously [4], the formation of apatite was enhanced using a re-immersion method in which the SBF was periodically replaced to maintain a high ionic concentration. Moreover, if a wollastonite bed is used as a calcium ion supplier during the first phase of immersion, the apatite nucleation is more effective [5,6].…”

Section: Introductionmentioning

confidence: 92%

Biomimetic Magnetic Nanoparticles for Hyperthermia Treatment

Múzquiz-Ramos¹,

Cortés-Hernández²,

Sánchez-Torres³

et al. 2011

KEM

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The aim of this work was the synthesis of bioactive magnetic particles (BMP) which are expected to form a thin apatite layer on its surface that may bond to bone with the osseous carcinogen tissue. Magnetite and Mg0.6Ca0.4Fe2O4 nanoparticles were obtained by a reverse co-precipitation and sol-gel methods, respectively. Magnetite particles were coated with chitosan in order to obtain a stable ferrofluid. Then both ferrites were biomimetically treated using two different simulated body fluids (SBF and 1.5 SBF). An apatite layer was formed on both types of BMP after the biomimetic treatment. Both ferrites showed superparamagnetic behavior before and after the apatite formation. Their time-dependent temperature profiles were measured under the effect of an AC magnetic field (AMF). After less than 20 min of applying the AMF an appropriate temperature for hyperthermia treatment was obtained. No citotoxicity was observed after osteosarcoma cell culture testing of BMP. Furthermore, after applying an AMF to the cells in contact with the BMP, the cells viability decreased considerably.

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“…3c,f) is demonstrated. According to the EDS analysis a compound with a Ca/P ratio = 1.3 was obtained, which may correspond to octacalcium phosphate (OCP) (22). It can be observed that the incorporation of pseudowollastonite particles promote the growth of the bioactive layer.…”

Section: P J Reséndiz-hernández D a Cortés-hernández M M G Smentioning

confidence: 99%