Bone Tumors and Tumor-like lesions: A study in a Tertiary Care Hospital, Mumbai

Abstract

Background: Bone tumors are one of the intimidate challenge to the orthopedic surgeon. This call out for even more concern in resource poor settings, in economically developing nations. We analysed bone tumours and tumour like lesions, their demographic features like age and sex distributions, anatomical sites of occurrence and their relative frequencies,clinico-pathological characteristics and histo-morphological features as seen in a tertiary care hospital of India.Methods: This is a retrospective study of 10 years in our department, of 216 cases of bone tumors, including primary bone tumors, metastatic lesions and tumor like lesions.Results: A total of 216 patients were studied aged 1 to 80 years. 114 (52.78%) patients were males and 102(47.22%) were females. Commonest bone tumor observed in our study was metastatic tumors 40/216 cases (18.52%).Commonest benign tumor in our study was osteochondroma 30/103 cases (29.13%) followed by giant cell tumor 27/103 cases (26.21 %). Commonest Primary malignant bone tumor in our study was Ewing's tumor 11/48 cases (22.92%), followed by osteogenic sarcoma and myeloma 9 cases (18.75%) each. Fibrous dysplasia was seen to be commonly located at jaw bone and skull region 6/13 cases (46.15%) whereas aneurysmal bone cyst was located commonly at vertebra 6/10 cases (60%). Out of 40 cases of metastatic bone tumors, 15 cases (37.5%) showed metastasis from lung carcinoma, of which, non-small cell carcinoma made up of 80 % of the cases. Conclusion:Metastatic lesion is commonest bone tumor in our study. Commonest benign tumor was osteochondroma and giant cell tumor. Ewing's tumor is commonest primary bone tumor and fibrous dysplasia in tumor like lesions of the bone.

Study of clinical, radiological, and histopathological features of bone lesions- A two-year study

“…These findings correlated well with the previous studies done by Bamnikar SA et al, Jain K et al, Baena Ocampo LC et al [12][13][14]. Pain and swelling (9 cases, 30.00%) was the most common overall clinical presentation as similar to Kumavat et al and Kokode [11,15]. In this further 50% of benign bone, tumors had pain and swelling while 21.43% of malignant tumors had pain and swelling.…”

“…The present study found an equal incidence of malignant bone tumors & benign bone tumors which is variable with the study done by Mohammad and Isa [10]. A commonest benign tumor in the current study was osteochondroma which is comparable with the study conducted by Kumavat et al and Bamanikar et al followed by multiple myeloma which is in concordance with the study by Jain et al [11][12][13]. The lesions ranged from 8-64 years with a mean age of 33.17 years.…”

A study of Giant Cell Lesions of Bone

“…According to Kumavat et al [13] out of 216 cases of bone tumors Out of 216 cases, primary bone tumors were 151 (69.91%), metastatic tumors were 40 cases (18.52%) and tumor like conditions were 25 cases (11.58%). According to Sunita A.Bamanikar et.…”

Evaluation of neoplastic bone lesions: A morphological study at a tertiary care centre.

“…4 Beside these all the histopathology provides accuracy in diagnosing these bone tumors or tumor like lesions. 5 Bone lesions may create diagnostic challenges to orthopaedic surgeons and surgical pathologists 6 , as the normal is composed of four types of elements including osteoid, cartilage, fibrous tissue and bone marrow, among which any element may be responsible for various benign and malignant neoplastic lesions. 7 Due to large variety of bone disorders, the exact diagnosis is very difficult clinically, and only exception to melanoma, the biochemical analysis is not much significant.…”