“…[17][18][19][20] Prophylactic antibiotics, antiseptics, and antifungal agents have been used to reduce microbial colonization of the ocular surface and the associated risk of microbial keratitis and/or endophthalmitis. [21][22][23][24][25] There is no evidence-based consensus on the composition or duration of an optimal postkeratoprosthesis prophylactic regimen. 5,[17][18][19][20][21][22][23][24][25] The prolonged use of soft contact lenses may be associated with an increased risk of gram-negative keratitis, 26,27 especially in this population with a high burden of ocular surface disease (OSD).…”