Botanical Drugs in Traditional Chinese Medicine With Wound Healing Properties

Abstract

Chronic and unhealed wound is a serious public problem, which brings severe economic burdens and psychological pressure to patients. Various botanical drugs in traditional Chinese medicine have been used for the treatment of wounds since ancient time. Nowadays, multiple wound healing therapeutics derived from botanical drugs are commercially available worldwide. An increasing number of investigations have been conducted to elucidate the wound healing activities and the potential mechanisms of botanical drugs in recent years. The aim of this review is to summarize the botanical drugs in traditional Chinese medicine with wound healing properties and the underlying mechanisms of them, which can contribute to the research of wound healing and drug development. Taken together, five botanical drugs that have been developed into commercially available products, and 24 botanical drugs with excellent wound healing activities and several multiherbal preparations are reviewed in this article.

Sanchi-mediated inactivation of IL1B accelerates wound healing through the NFκB pathway deficit

“…Unhealed wound is a serious public problem, which brings economic burdens and psychological pressure to patients, and various herbal drugs in traditional Chinese medicine have been applied for wound healing since ancient times [ 22 ]. Herein, we successfully prepared hydrogel containing Sanchi extract capable of promoting wound healing in a rat model.…”

Developing Chinese herbal-based functional biomaterials for tissue engineering

“…1 C). Centella asiatica promotes the proliferation of fibroblasts, increases the synthesis of collagen, and inhibits inflammation, thus promoting wound healing [ 18 ]. Owing to its excellent wound-healing properties, researchers have developed various wound dressings containing Centella asiatica , all of which have shown excellent wound-healing activity, suggesting their potential use as wound-healing agents [ 19 , 20 ].…”

Moringa oleiferaLam.: a comprehensive review on active components, health benefits and application

“…Besides the use of chemical drugs, high prices, side effects and other problems, herbal remedies have attracted attention. 110 M. oleifera is widely used in wound treatment due to its low side effects and excellent antioxidant and antibacterial activity. In addition to the above functions, M. oleifera can also be used for bone protection, 91 promote coagulation 111 and so on.…”