Botanical Medicines

McKenna, Dennis J.; Hughes, Kerry; Jones, K. K.

doi:10.4324/9780203048368

Cited by 14 publications

(13 citation statements)

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“…Certain bioactive compounds play the major role in enhancing testosterone levels endogenously and for boosting the sexual behavior in males. These compounds work by special mechanism which includes: steroids by promoting androgen production [32,33] alkaloids through widening the blood vessels in the reproductive organs, saponins through stimulating gonadal tissue and CNS by means of NO based mechanism [34] flavonoids by increasing testosterone synthesis or by preventing its metabolic deterioration [35,36] Steroids are one of the dominant components of Ganoderma lucidum [11]. Thus, the enhancement in sexual activity exhibited in the present study may be due to the presence of steroids in GLE.…”

Section: Discussionmentioning

confidence: 63%

“…From the fruiting bodies, spores, and mycelia of reishi, various types of bioactive compounds have been identified which commonly consist of proteins, peptides, triterpenoids, sterols, polysaccharides, steroids, nucleotides and trace elements [11,12]. Ganoderma lucidum has shown various pharmacological activities which include antiviral (anti-HIV), hepatoprotective, anti-ulcer antibacterial, anti-tumour, anti-inflammatory, radio-protective, age promoting, analgesic, hypolipidemic, sleep promoting, cytotoxic, chemopreventive, antifibrotic, antiatherosclerotic, antidiabetic, radical scavenging and antioxidative properties [8,11,[13][14][15][16]. In this study, we have evaluated the potential aphrodisiac activity of ethanol extract of Ganoderma lucidum (GLE) in male Wistar rats.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of aphrodisiac activity of ethanol extract of Ganoderma lucidum in male Wistar rats

Ahmed

Aslam

2018

Clin Phytosci

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Background: Ganoderma lucidum was traditionally used to manage male sexual dysfunction. This study was designed to investigate and establish the traditional aphrodisiac potential of the herb. Methods: Aphrodisiac potential was evaluated following the oral administration of two different doses (150 and 300 mg/kg) of ethanol extract of Ganoderma lucidum. Sildenafil citrate (Viagra) and distilled water were used as positive and negative controls respectively. Mounting, intromission and ejaculation frequencies, mating performance, and orientation activities towards females, towards the environment, and towards self were observed. Serum testosterone levels were also evaluated. Results: The results of the study show that the extract has significantly increased the mounting behavior and mating performance of the rats. There was also significant increase in the number of intromissions and ejaculations. The rats treated with extract were more interested in female rats as indicated by significant increase in the number of anogenital sniffing and climbing. Serum testosterone levels were also significantly increased in the treatment groups. Conclusion: Ethanol extract of Ganoderma lucidum possesses aphrodisiac activity in male Wistar rats. The lower dose of 150 mg/kg was more effective in terms of aphrodisiac potential of the extract.

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Section: Discussionmentioning

confidence: 63%

Section: Introductionmentioning

confidence: 99%

Evaluation of aphrodisiac activity of ethanol extract of Ganoderma lucidum in male Wistar rats

Ahmed

Aslam

2018

Clin Phytosci

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“…It is widely used in China as a remedy for minor health disorders to promote vitality and longevity. In East Asia, it has been long used to treat many diseases such as nephritis, chronic hepatitis, gastric ulcers, arthritis, neurasthenia, bronchitis, asthma, and hypertension in oriental countries [ 1 – 5 ]. Recent studies on G .…”

Section: Introductionmentioning

confidence: 99%

Utilization of Response Surface Methodology in Optimization of Polysaccharides Extraction from Vietnamese Red Ganoderma lucidum by Ultrasound-Assisted Enzymatic Method and Examination of Bioactivities of the Extract

Dat

Lam

Nguyen

et al. 2021

The Scientific World Journal

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Red Ganoderma lucidum (G. lucidum) is a popular medicinal herb commonly used in Vietnamese traditional remedies due to its potential value for health. In this study, polysaccharides were extracted from G. lucidum using ultrasound-assisted enzymatic extraction method. The response surface methodology and Box–Behnken design were employed to investigate the effects of pH, extraction temperature, extraction time, and ultrasonic power on the content of polysaccharides. Based on ultraviolet-visible spectroscopy analysis, the highest content of polysaccharides in the extract was 32.08 mg/g under optimum experimental parameters including enzyme concentration of 3%, pH of 5.5, extraction temperature of 45°C, extraction time of 30 min, and ultrasonic power of 480 W. The Fourier-transform infrared spectroscopy was also used to identify the functional groups in the extracts. The molecular weights of polysaccharides were determined by gel permeation chromatography. The obtained extract was then evaluated for anticancer activities by using (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay, showing the anticancer activities with the half-maximal inhibitory concentration value of more than 512 μg/mL. This result suggested that UAEE could be considered as an appropriate and effective extraction method for bioactive crude polysaccharides from G. lucidum.

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“…Reishi remained a traditional therapy for shortness of breath, palpitation, dizziness, and insomnia (Wachtel‐Galor et al, 2011). Besides, Reishi found numerous applications in treating hepatitis, arthritis, asthma, insomnia, gastric ulcers, and neurasthenia (González et al, 2020; McKenna, 2002; Zahid, Barua, & Huq, 2010; S. Zhou & Gao, 2002). Traditionally, Reishi has been used after boiling and drying for the treatment of various ailments (Cho et al, 2012).…”

Section: Literature Reviewmentioning

confidence: 99%

Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and toxicological properties

Ahmad

Riaz

Khan

et al. 2021

Phytotherapy Research

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Reishi owes an exceptional value in nutritional, cosmeceutical, and medical treatments; however, none of the studies has provided its future-driven critical assessment. This study documents an up-to-date review (2015-2020, wherever applicable) and provide valuable insights (preclinical and clinical evidence-based) with comprehensive and critical assessments. Various databases 'Google scholar', 'Web of Science', 'ScienceDirect', 'PubMed', 'Springer Link', books, theses

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Botanical Medicines

Cited by 14 publications

References 0 publications

Evaluation of aphrodisiac activity of ethanol extract of Ganoderma lucidum in male Wistar rats

Evaluation of aphrodisiac activity of ethanol extract of Ganoderma lucidum in male Wistar rats

Utilization of Response Surface Methodology in Optimization of Polysaccharides Extraction from Vietnamese Red Ganoderma lucidum by Ultrasound-Assisted Enzymatic Method and Examination of Bioactivities of the Extract

Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and toxicological properties

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