Bottom-up microwave-assisted seed-mediated synthesis of gold nanoparticles onto nanocellulose to boost stability and high performance for SERS applications

Marques, Ana C.; Pinheiro, Tomás; Morais, Maria; Martins, Carla F.; Andrade, Ana Francisca; Martins, Rodrigo; Sales, M. Goreti F.; Fortunato, Elvira

doi:10.1016/j.apsusc.2021.150060

Cited by 19 publications

(10 citation statements)

References 74 publications

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“…With this platform, preliminary results on the label-free screening of S protein were reported, through the identification of characteristic bands of proteins. 119 …”

Section: Paper-based Diagnostics For Viral Pathogen Detectionmentioning

confidence: 99%

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Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

et al. 2021

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The appearance and quick spread of the new severe acute respiratory syndrome coronavirus disease, COVID-19, brought major societal challenges. Importantly, suitable medical diagnosis procedures and smooth clinical management of the disease are an emergent need, which must be anchored on novel diagnostic methods and devices. Novel molecular diagnostic tools relying on nucleic acid amplification testing have emerged globally and are the current gold standard in COVID-19 diagnosis. However, the need for widespread testing methodologies for fast, effective testing in multiple epidemiological scenarios remains a crucial step in the fight against the COVID-19 pandemic. Biosensors have previously shown the potential for cost-effective and accessible diagnostics, finding applications in settings where conventional, laboratorial techniques may not be readily employed. Paper- and cellulose-based biosensors can be particularly relevant in pandemic times, for the renewability, possibility of mass production with sustainable methodologies, and safe environmental disposal. In this review, paper-based devices and platforms targeting SARS-CoV-2 are showcased and discussed, as a means to achieve quick and low-cost PoC diagnosis, including detection methodologies for viral genomic material, viral antigen detection, and serological antibody testing. Devices targeting inflammatory markers relevant for COVID-19 are also discussed, as fast, reliable bedside diagnostic tools for patient treatment and follow-up.

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“…With this platform, preliminary results on the label-free screening of S protein were reported, through the identification of characteristic bands of proteins. 119 …”

Section: Paper-based Diagnostics For Viral Pathogen Detectionmentioning

confidence: 99%

“…More recently, Marques et al reported a SERS platform based on a nanocellulose substrate, obtained from nata de coco cubes, with in-situ grown gold nanoparticles, assisted by microwave irradiation. With this platform, preliminary results on the label-free screening of S protein were reported, through the identification of characteristic bands of proteins 119.…”

mentioning

confidence: 99%

Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

et al. 2021

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“…Moreover, the use of these substrates allows the production of sensing devices that are sustainable and recyclable . These substrates are very versatile and have been used in various applications, including the development of sensing devices based on optical − or electrochemical measurements . The ZnO nanostructures are the basis of the developed glucose sensor, in which the addition of glucose to the nanorods is followed by UV irradiation, which stimulates the monosaccharide’s photo-oxidation.…”

Section: Introductionmentioning

confidence: 99%

Visible Photoluminescent Zinc Oxide Nanorods for Label-Free Nonenzymatic Glucose Detection

Morais

Marques

Ferreira

et al. 2022

ACS Appl. Nano Mater.

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Diabetes mellitus affects a significant percentage of the world’s population, and the incidence of this disease is expected to increase exponentially in the coming years. The development of practical and low-cost glucose sensors is of utmost importance to monitor and manage diabetes and diabetes associated complications. In this scope, a nonenzymatic glucose sensor was produced by growing zinc oxide (ZnO) nanorods on a cellulose-based substrate by microwave-assisted hydrothermal synthesis. The developed sensor relies on ZnO nanorods’ photocatalytic ability to photo-oxidize glucose, eliminating the need to use an oxidase enzyme. The quantification of glucose is based on the quenching of the ZnO’s photoluminescence signal by the hydrogen peroxide produced during the nonenzymatic oxidation of this monosaccharide. The developed sensor possesses a sensitivity of 1.46%/mM, a linear range between 0.5 and 30 mM, and a limit of detection of 0.103 mM. The sensor showed good selectivity for glucose, and it was also demonstrated that there was a high correlation between the glucose concentration values obtained using the sensor’s calibration curve and the clinical data of human plasma samples, therefore validating the use of ZnO nanorods to monitor the glucose concentration in human plasma samples. This work reports for the first time a ZnO-based eco-friendly, stable, and highly selective alternative for glucose monitoring, pointing to a promising future for metal oxide nanostructures for biomedical sensors.

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“…Coronavirus disease (COVID-19) has caused the global outbreak with millions of deaths, and the death toll is still rising. Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is the pathogen of COVID-19, which has an envelope structure and contains genetic substrate of single positive-stranded RNA [ [1] , [2] , [3] ]. The virus is a β coronavirus derived from bats, and phylogenetic studies have shown that it may infect humans and spread among human hosts through other intermediate hosts [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Nanobody-based label-free photoelectrochemical immunoassay for highly sensitive detection of SARS-CoV-2 spike protein

Chen

Duan

et al. 2022

Analytica Chimica Acta

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Bottom-up microwave-assisted seed-mediated synthesis of gold nanoparticles onto nanocellulose to boost stability and high performance for SERS applications

Abstract: Bottom-up microwave-assisted seed-mediated synthesis of gold nanoparticles onto nanocellulose to boost stability and high performance for SERS applications,

Cited by 19 publications

References 74 publications

Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

Visible Photoluminescent Zinc Oxide Nanorods for Label-Free Nonenzymatic Glucose Detection

Nanobody-based label-free photoelectrochemical immunoassay for highly sensitive detection of SARS-CoV-2 spike protein

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