Botulinum toxin type A injection in the treatment of acquired symmetrical acrokeratoderma: One case report

Abstract

Acquired symmetrical acrokeratoderma (SAK) is a rare dermatosis more frequently reported in East Asians. It is characterized by brownish, hyperkeratotic plaques on the wrists, dorsal hands, fingers and feet, sparing palmoplantar area. 1 Lesions become whitish after water immersion or sweating, and improve partially in winter. Although it is generally asymptomatic, cosmetic concern may bother the patients. Current treatment choices, including topical tretinoin, glucocorticoid, keratolytic or systemic acitretin, only provide poor or partial improvement. 1,2

Symmetrical acrokeratoderma: a case series

“…Skin texture, thickness, pigmentation and extent of lesions were improved after five weeks therapy of botulinum toxin. 15,16…”

Symmetrical Acrokeratoderma: A Case Report and Literature Review

“…Meanwhile, the skin texture, thickness, pigmentation and extent of lesions were significantly improved, and previously affected area did not turn whitish after sweating or bathing after administration of therapy for five weeks. 18 , 19 …”