Botulism: The Present Status of the Disease

Hatheway, Charles L.

doi:10.1007/978-3-642-85173-5_3

Cited by 108 publications

(100 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…All forms of botulism disease are characterized by flaccid paralysis of peripheral muscles resulting from the specific action of boNT at the neuromuscular junctions (16). boNT/A is the serotype most frequently involved in human botulism in the United States (3) and the second most common cause of botulism in Italy and Europe (36).…”

Section: Botulinum Neurotoxin (Bont) Type a (Bont/a) Is One Of The Sementioning

confidence: 99%

Differentiation of the Gene Clusters Encoding Botulinum Neurotoxin Type A Complexes in Clostridium botulinum Type A, Ab, and A(B) Strains

Franciosa¹,

Floridi²,

Maugliani³

et al. 2004

Appl Environ Microbiol

View full text Add to dashboard Cite

We describe a strategy to identify the clusters of genes encoding components of the botulinum toxin type A (boNT/A) complexes in 57 strains of Clostridium botulinum types A, Ab, and A(B) isolated in Italy and in the United States from different sources. Specifically, we combined the results of PCR for detecting the ha33 and/or p47 genes with those of boNT/A PCR-restriction fragment length polymorphism analysis. Three different type A toxin gene clusters were revealed; type A1 was predominant among the strains from the United States, whereas type A2 predominated among the Italian strains, suggesting a geographic distinction between strains. By contrast, no relationship between the toxin gene clusters and the clinical or food source of strains was evident. In two C. botulinum type A isolates from the United States, we recognized a third type A toxin gene cluster (designated type A3) which was similar to that previously described only for C. botulinum type A(B) and Ab strains. Total genomic DNA from the strains was subjected to pulsed-filed gel electrophoresis and randomly amplified polymorphic DNA analyses, and the results were consistent with the boNT/A gene clusters obtained.

show abstract

Section: Botulinum Neurotoxin (Bont) Type a (Bont/a) Is One Of The Sementioning

confidence: 99%

Differentiation of the Gene Clusters Encoding Botulinum Neurotoxin Type A Complexes in Clostridium botulinum Type A, Ab, and A(B) Strains

Franciosa¹,

Floridi²,

Maugliani³

et al. 2004

Appl Environ Microbiol

View full text Add to dashboard Cite

show abstract

“…This process can take up to eight months. [1][2][3] The classical presentation of Clostridium botulism is one of an acute, afebrile, descending paralysis beginning with cranial nerve abnormalities as early as eight hours after exposure. There are no sensory deficits and deep tendon reflexes may be preserved early on.…”

mentioning

confidence: 99%

Paralysie aiguë après une «mauvaise patate» un cas de botulisme

Bhutani

Ralph

Sharpe

2005

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

“…An average of 450 outbreaks of foodborne botulism with 930 cases have been reported annually worldwide [47]. The main habitat of clostridia is the soil but they are also found in sewage, rivers, lakes, sea water, fresh meat, and fish [48,49].…”

Section: Listeria Monocytogenes Staphylococcus Aureus Clostridium Pmentioning

confidence: 99%

Lactic Acid Bacteria and Their Bacteriocins: A Promising Approach to Seafood Biopreservation

Ghanbari¹,

Jami²

2013

Lactic Acid Bacteria - R &Amp; D for Food, Health and Livestock Purposes

View full text Add to dashboard Cite

Botulism: The Present Status of the Disease

Cited by 108 publications

References 42 publications

Differentiation of the Gene Clusters Encoding Botulinum Neurotoxin Type A Complexes in Clostridium botulinum Type A, Ab, and A(B) Strains

Differentiation of the Gene Clusters Encoding Botulinum Neurotoxin Type A Complexes in Clostridium botulinum Type A, Ab, and A(B) Strains

Paralysie aiguë après une «mauvaise patate» un cas de botulisme

Lactic Acid Bacteria and Their Bacteriocins: A Promising Approach to Seafood Biopreservation

Contact Info

Product

Resources

About