Bovine oocyte and embryo development following meiotic inhibition with butyrolactone I

Lonergan, Patrick; Dinnyés, András; Fair, Trudee; Yang, Xiangzhong; Boland, M.P.

doi:10.1002/1098-2795(200010)57:2<204::aid-mrd12>3.0.co;2-n

Cited by 90 publications

(75 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous published data has shown fresh oocyte IVF cleavage rates of up to 80% [10]. An appropriate future study would be to evaluate the cryoloop vitrification technique in mature mouse oocytes.…”

Section: Resultsmentioning

confidence: 99%

Cryopreservation of bovine oocytes: is cryoloop vitrification the future to preserving the female gamete?

Mavrides

Morroll

2002

Reprod. Nutr. Dev.

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Cryopreservation of bovine oocytes: is cryoloop vitrification the future to preserving the female gamete?

Mavrides

Morroll

2002

Reprod. Nutr. Dev.

View full text Add to dashboard Cite

“…One route towards improving embryo yield may be the prematuration of the oocyte prior to maturation. While some recent results are encouraging in that oocytes can be reversibly maintained at the germinal vesicle stage without affecting subsequent blastocyst yield [41,47,50,55,57], it has not yet been demonstrated that such an approach can improve the developmental ability of an oocyte. In addition, there is little if any evidence to demonstrate that such blocked oocytes can result in the birth of normal offspring.…”

Section: Resultsmentioning

confidence: 99%

Factors influencing oocyte and embryo quality in cattle

et al. 2001

Self Cite

View full text Add to dashboard Cite

“…The effects of various kinase inhibitors on embryo development following IVM and IVF are summerized in Table 5. These studies show that controlling spontaneous meiotic progression by manupilating MPF activity, either adversely affects [58,68] or has no positive effect [59,60,77,78] on subsequent oocyte developmental competence after IVF except for our data (Fig. 7) [79].…”

mentioning

confidence: 77%

“…To improve the developmental competence of bovine immature oocytes, various approaches have been attempted. Several studies have examined the effects of holding oocytes at the germinal vesicle (GV) stage before in vitro maturation, because oocytes might require time to acquire developmental competence during meiotic arrest [58][59][60]. This idea is based on the fact that mammalian oocytes are arrested at the diplotene stage until the GnRH surge occurs and meiotic maturation resumes.…”

Section: Meiotic Arrestmentioning

confidence: 99%

Application of In Vitro Maturation to Assisted Reproductive Technology

Hashimoto¹

2009

J. Reprod. Dev.

View full text Add to dashboard Cite

Abstract. In vitro maturation (IVM) of immature oocytes is an important reproductive technology that generates mature oocytes that are capable of supporting preimplantation embryo development and full development to turm. The developmental competence of oocytes after in vitro fertilization (IVF) was supported in cumulus-cell density dependent manner. The developmental competence of oocytes matured under low oxygen (5% O2) tension was higher than that of oocytes matured under high oxygen tensinon (20% O2) due to the decrease of reactive oxygen content in the oocyte. To expand the availability of female gamete, an attempt to culture the growing oocytes have been made. We have focused attention on the mitochondrial activity of in vitro grown (IVG) oocytes and shown that L-Carnitine, which acts as a carrier of fatty acids across the inner mitochondrial membrane for subsequent β-oxidation, supported the viability of growing oocytes. Nowadays, IVM is gaining acceptance in assisted reproductive technology in cattle and human. Key words: Cumulus cell density, Meiotic arrest, Mitochondrial activity of growing oocytes, Oocyte transportation, Transvaginal oocyte pick up (J. Reprod. Dev. 55: [1][2][3][4][5][6][7][8][9][10] 2009) nimal breeders, especially cattle breeders have been trying to get as many offspring from their genetically superior or important animals as possible. Thus, hormonal induction of multiple ovulations, followed by non-surgical collection of the embryos and embryo transfer to recipients is widely used. This multiple ovulation and embryo transfer procedure can be repeated in the same animal about 4 times per year in cattle. However, the yield of transferable embryos is highly variable. No more than an average of 20 embryos per year per animal can be obtained in cattle [1]. Feedback on the endocrinological regulation of follicle growth and maturation also limits the number of oocytes that can mature and develop in vivo [2]. Thus embryo production in vivo by means of super-ovulation may lead to less than 100 embryos over the lifespan of an individual cow, whereas approximately 100,000 gametes are present in the ovaries. If more gametes could be matured, fertilized and developed in vitro, production would increase correspondingly. Oocytes from slaughterhouse ovaries [3][4][5] have been used for the production of bovine embryos in vitro. Moreover, in vitro embryo production from live cows has been established [6]. However, the ability of bovine oocytes matured in vitro to develop to the morula/blastocyst stage is less than that of in vivo-matured oocytes [7,8]. The decrease in the developmental competence of in vitro-matured oocytes may be due to insufficient cytoplasmic maturity.In this paper, 1) bovine oocyte-pick-up (OPU) from live cows, 2) transportation of bovine immature oocytes, 3) improvement of in vitro maturation (IVM) of bovine immature oocytes, 4) application of IVM culture to human assisted reproductive technology (ART), 5) IVM following meiotic inhibition with butyrolactone I under low oxyg...

show abstract

Bovine oocyte and embryo development following meiotic inhibition with butyrolactone I

Cited by 90 publications

References 21 publications

Cryopreservation of bovine oocytes: is cryoloop vitrification the future to preserving the female gamete?

Cryopreservation of bovine oocytes: is cryoloop vitrification the future to preserving the female gamete?

Factors influencing oocyte and embryo quality in cattle

Application of In Vitro Maturation to Assisted Reproductive Technology

Contact Info

Product

Resources

About