Bowenoid papulosis: clinical and histological study of eight cases.

Gimeno, Enrique; Vilata, J.J.; Sánchez, Jorge; Lloret, A.; Fortea, José M.

doi:10.1136/sti.63.2.109

Cited by 15 publications

(17 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…89 BP tumor cells are large, hyperchromatic, pleomorphic keratinocytes that demonstrate a loss of cellular polarity. 90 Cells are often multinucleated and necrotic with abnormal maturation from the basal layer to the granular cell layer. Mitoses, some atypical, are often visible during metaphase.…”

Section: Bowenoid Papulosismentioning

confidence: 99%

See 1 more Smart Citation

Viral-Associated Nonmelanoma Skin Cancers: A Review

Dubina¹,

Goldenberg²

2009

The American Journal of Dermatopathology

View full text Add to dashboard Cite

Nonmelanoma skin cancers are the most common malignancies in the United States, with over 1.3 million patients diagnosed yearly. Several types of nonmelanoma skin cancer and precancerous lesions have an associated viral pathogenesis, including epidermodysplasia verruciformis, verrucous carcinoma, bowenoid papulosis, Kaposi sarcoma, squamous cell carcinoma, and, most recently, Merkel cell carcinoma. It is now widely accepted that high-risk human papillomaviruses (HPVs) play a key role in pathogenesis of cervical and anogenital cancer. Currently, 108 types of HPV have been discovered. They can be divided into genera including alpha, beta, and gamma HPVs, which comprise the majority of cutaneous HPVs. The relationship between viruses and cancer is a popular focus of research in an era of AIDS and organ transplantation, where immunosuppression is not uncommon. The incidence of viral-related malignancies in these populations is increasing. Because of the widespread nature of these cutaneous malignancies, an evaluation of these conditions is valuable. This review of the literature will focus on the histologic aspects of viral-associated skin malignancies, as well as the epidemiology, etiology, and clinical aspects of these diseases.

show abstract

Section: Bowenoid Papulosismentioning

confidence: 99%

“…Capillaries are often dilated with surrounding edema. 90 Immunoperoxidase staining may reveal the presence of papillomavirus antigen in the nuclei of superficial epidermal cell. 90 Electron microscopy demonstrates a decreased number of intact desmosomes and tonofilament aggregation causing dyskeratosis.…”

Section: Bowenoid Papulosismentioning

confidence: 99%

Viral-Associated Nonmelanoma Skin Cancers: A Review

Dubina¹,

Goldenberg²

2009

The American Journal of Dermatopathology

View full text Add to dashboard Cite

show abstract

“…Ablative treatment carries a risk of post‐operative anal stenosis. Local imiquimod has been used successfully 52 . It is not clear whether the treatment of AIN reduces the risk of developing PAC.…”

Section: Carcinomasmentioning

confidence: 99%

Anogenital malignancies and pre‐malignancies

Henquet¹

2011

Acad Dermatol Venereol

View full text Add to dashboard Cite

Anogenital pre-malignancies and malignancies are frequently encountered. Aetiopathogenetically, human papillomavirus (HPV) infection plays a critical role. However, there is a variable degree of association of HPV infection with the development of anogenital malignancies. In this context, the high level of clinically unapparent HPV infection should be considered. Therefore, the question arises if the association with HPV is always causative. Besides HPV, pre-existent lichen sclerosus is also an important aetiopathologic factor in the development of anogenital malignancies. Common anogenital pre-malignancies comprise Bowen's disease (BD), Bowenoid papulosis (BP) and erythroplasia of Queyrat (EQ). From a clinical point of view, these are clearly different entities, but from a histopathological point of view, BD, BP and EQ are indistinguishable. They all represent forms of squamous intraepithelial neoplasia (IN). Intraepithelial neoplasia (IN) is not only restricted to squamous variants, but also includes non-squamous IN, Paget's disease (PD) and melanoma in situ. The risk of developing anogenital (pre)malignancies or other tumours is higher in immunocompromised and immunodeficient patients, in particular those suffering from human immunodeficiency virus (HIV) infection. Such risk factors will affect treatment and follow-up modalities. Regarding prophylactic measures, a relatively recent but very important development is the availability of HPV vaccination on a large scale. Momentarily, the effects of such vaccination, on a population-based scale, are not yet clear but will become apparent in the near future. Management of anogenital pre-malignancies and malignancies should be tailor-made and may be organized in a multidisciplinary fashion.

show abstract

“…As a routine, it may be wise to apply a topical anti-inflammatory remedy, such as a mild steroid-antimycotic cream, twice daily for a week or so to any acetowhite lesions of the outer genitals and subsequently repeat the test. Trauma or inflammatory acetowhite lesions will then disappear 125 ) be amalgamated into a category of low-grade CIN with CIN III remaining as high-grade CIN124.…”

Section: The Acetic Acid Testmentioning

confidence: 99%

Genitoanal Papillomavirus Infection: Diagnostic and Therapeutic Objectives in the Light of Current Epidemiological Observations

1991

Int J STD AIDS

View full text Add to dashboard Cite

Summary: During the past decade a wide span of heterogeneity has been demonstrated for human papillomaviruses (HPVs), and some basic properties of the HPV genome have been revealed. The use of hybridization assays for HPV DNA detection in infected epithelia, and the recent introduction of synthetic HPV peptides for detection of type-specific circulating antibodies, have resulted in a major rethinking of HPV epidemiology. Recent data indicate that various HPVs may be transmitted perinatally during early infancy and that a long latency with periodic reactivation seems to be quite common. The present review attempts to assess recent epidemiological data with the concept of genitoanal papillomavirus infection (GPVI) as a predominantly sexually transmitted disease. Some diagnostic and therapeutic aspects are outlined with a pragmatic approach to the clinical relevance of GPVI.

show abstract

Bowenoid papulosis: clinical and histological study of eight cases.

Cited by 15 publications

References 15 publications

Viral-Associated Nonmelanoma Skin Cancers: A Review

Viral-Associated Nonmelanoma Skin Cancers: A Review

Anogenital malignancies and pre‐malignancies

Genitoanal Papillomavirus Infection: Diagnostic and Therapeutic Objectives in the Light of Current Epidemiological Observations

Contact Info

Product

Resources

About