2021
DOI: 10.21203/rs.3.rs-435109/v1
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BPA and BPS Affect the Expression of Anti-Mullerian Hormone (AMH) and Its Receptor During Bovine Oocyte Maturation and Early Embryo Development

Abstract: Background Exposure to endocrine-disrupting chemicals, such as Bisphenol A (BPA) and Bisphenol S (BPS), is widespread and has negative implications on embryonic development. Preliminary evidence revealed that in women undergoing IVF treatment, urinary BPA levels were associated with low serum anti-Mullerian hormone, however a definitive relationship between the two has not yet been characterized. Methods This study aimed to evaluate BPA and BPS effects on in vitro oocyte maturation and early preimplantation … Show more

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“…Currently, there are plenty synthetic compounds that are found to contaminate in the environment, such as Bisphenol-A (BPA), Phatalate, Nonylphenol, and pesticides (36). BPA is one of the serious harmful substances, which have shown adverse effects not only in the reproductive system (37), but also other developmental systems (38,39). Though FDA has announced that the low-dose exposure of FDA is not harmful (40), the application in plasticware and their environmental contamination should be aware.…”
Section: Background and Rationalementioning
confidence: 99%
“…Currently, there are plenty synthetic compounds that are found to contaminate in the environment, such as Bisphenol-A (BPA), Phatalate, Nonylphenol, and pesticides (36). BPA is one of the serious harmful substances, which have shown adverse effects not only in the reproductive system (37), but also other developmental systems (38,39). Though FDA has announced that the low-dose exposure of FDA is not harmful (40), the application in plasticware and their environmental contamination should be aware.…”
Section: Background and Rationalementioning
confidence: 99%