Brain Imaging in Idiopathic Intracranial Hypertension

Bidot, Samuel; Saindane, Amit M.; Peragallo, Jason H.; Bruce, Bonnie; Newman, Nancy J.; Biousse, Valérie

doi:10.1097/wno.0000000000000303

Cited by 201 publications

(169 citation statements)

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“…Recently, however, some small changes such as empty sella, posterior globe flattening, intraocular protrusion of optic nerve, optic nerve tortuosity, distension of perioptic subarachnoid space, and transverse sinus stenosis have been reported to be indicative of PTCS (14). Empty sella is the most commonly reported finding in patients with IIH (15). Although empty sella is used for diagnosis in the literature, partial empty sella and thinned pituitary gland are also reported to be a common finding in these patients.…”

Section: Discussionmentioning

confidence: 99%

Clinical and Demographic Features of Pseudotumor Cerebri Syndrome Diagnosed in a University Hospital

Arslan¹,

Arıkanoğlu²,

Akıl³

2017

tnd

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Objective: Pseudotumor cerebri syndrome (PTCS) is characterized by symptoms and signs of increased intracranial pressure without ventriculomegaly, intracranial tumor or mass. This study aimed to explore and analyze 34 patients with PTCS according to age, sex, symptoms of the disorder, cranial magnetic resonance images findings, etiology, and treatment. Materials and Methods:A total of 34 patients who were diagnosed as having PTCS and followed up between January 2011 and August 2016 by Dicle University Medical School Neurology Department were included in this study. PTCS was diagnosed in accordance with the modified Dandy criteria. Results:Thirty-four patients were identified as having PTCS. Twenty-one (91.2%) had headache, 19 (55.9%) had blurred vision, 6 (17.6%) had diplopia, 2 (5.9%) had vertigo, 1 (2.9%) had tinnitus, and 1 (2.9%) had numbness of the face. Twenty-seven patients were diagnosed as having idiopathic intracranial hypertension, 21 (61.8%) had no etiologic factors. Six (17.6%) patients were obese, one of whom had recently gained weight and another had polycystic ovary syndrome. Seven patients were thought to have secondary PTCS with the following etiologic factors: 2 (5.9%) patients had Hashimoto's thyroiditis, 1 (2.9%) had a history of all-trans retinoic acid intake due to a malignancy, 1 (2.9%) had choroid plexus granuloma, 2 (5.9%) had sinus venous thrombosis, and 1 (2.9%) had Familial Meditteranian Fever.Conclusion: Although PTCS was described many years ago, its physiopathology and exact treatment procedures are not clearly understood. The most important target of its treatment is to prevent loss of vision and improve symptoms. With a better understanding of its pathophysiology, effective treatment protocols will be developed. Keywords: Idiopathic intracranial hypertension, pseudotumor cerebri syndrome, headacheAmaç: Psödotümör serebri sendromu (PTSS) ventrikülomegali, intrakraniyal tümör veya kitle olmaksızın intrakraniyal basıncın (İKB) arttığı bir sendromdur. Bu çalışmada kliniğimizde PTSS tanısı ile takip edilen 34 hastanın yaş, cinsiyet dağılımı, semptomları, kraniyal manyetik rezonans görüntüleme bulguları, etiyolojileri ve tedavileri tartışılmaktadır. Gereç ve Bulgular:Olguların 31'inde (%91,2) baş ağrısı, 19'unda (%55,9) bulanık görme, 6'sında (%17,6) diplopi, 1'inde (%2,9) tinnitus, 1'inde (%2,9) yüzde uyuşma, 2'sinde (%5,9) vertigo yakınması vardı. Yirmi yedi hasta idiyopatik intrakraniyal hipertansiyon (İİH) olarak kabul edildi. Yirmi bir hastada (%61,8) etiyoloji saptanamadı. Altı hastada (%17,6) obezite, bunların 1 tanesinde yakın zamanda kilo alma öyküsü, 1 tanesinde de polikistik over sendromu saptandı. Yedi hastada sekonder PTSS düşünüldü. Sekonder sebepler olarak; 2 hastada (%5,9) Hashimoto tiroiditi, 1 hastada (%2,9), malignite nedeniyle all-trans retinoik asit kullanımı, 1 hastada (%2,9) koroid pleksus granülomu, 2 hastada (%5,9) sinüs trombozu, 1 hastada (%2,9) Ailesel Akdeniz Ateşi etiyolojik neden olarak saptandı. Clinical and Demographic Features of Pseudotumor

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Section: Discussionmentioning

confidence: 99%

Clinical and Demographic Features of Pseudotumor Cerebri Syndrome Diagnosed in a University Hospital

Arslan¹,

Arıkanoğlu²,

Akıl³

2017

tnd

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“…according to [37] protocol should include venous angiography either using the "time of flight" (TOF) technique or preferably as contrast-enhanced MR venography (CE-MRV) [42]. The described changes after lumbar puncture are typically fully reversible [40].…”

Section: Idiopathic Intracranial Hypertensionmentioning

confidence: 99%

Diagnosis and Differential Diagnosis of Hydrocephalus in Adults

Langner

Fleck

Baldauf

et al. 2017

Fortschr Röntgenstr

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ABSTR AC TPurpose Hydrocephalus is caused by an imbalance of production and absorption of cerebrospinal fluid (CSF) or obstruction of its pathways, resulting in ventricular dilatation and increased intracranial pressure. Imaging plays a crucial role in the diagnosis, differential diagnosis and planning of treatment.Methods This review article presents the different types of hydrocephalus und their typical imaging appearance, describes imaging techniques, and discusses differential diagnoses of the different forms of hydrocephalus. Results and Conclusion

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“…Patofysiologisk mekanisme og årsaksforhold ved slike stenoser er ikke tilstrekkelig belyst. Asymmetrisk kaliber av sinus transversus mellom høyre og venstre side innebaerer ofte ikke noe patologisk og er vanlig hos friske, mens enkelte hevder at Antatt idiopatisk intrakranial hypertensjon uten papillødem B+C+D+E Minst 3 radiologiske tegn på høyt intrakranialt trykk 1 manglende stenosering av sinusvenene kan vaere en grunn til å revurdere diagnosen idiopatisk intrakranial hypertensjon (1,14). Andre MR-funn som assosieres med tilstanden er såkalt tom sella (empty sella) og forandringer relatert til n. opticus og avflating av bakre øyepol (fig 2b -d).…”

Section: Bildediagnostikkunclassified

“…Andre MR-funn som assosieres med tilstanden er såkalt tom sella (empty sella) og forandringer relatert til n. opticus og avflating av bakre øyepol (fig 2b -d). Ingen MRfunn har kombinert høy sensitivitet og spesifisitet, og få har studert prediktiv verdi av kombinasjoner av radiologifunn (14). I en studie med barn med idiopatisk intrakranial hypertensjon fant man at kombinasjonen av tre eller flere MR-funn (sinusvenestenose ikke inkludert) hadde en sensitivitet på 45 % og en spesifisitet på 95 % (14).…”

Section: Bildediagnostikkunclassified

“…Ingen MRfunn har kombinert høy sensitivitet og spesifisitet, og få har studert prediktiv verdi av kombinasjoner av radiologifunn (14). I en studie med barn med idiopatisk intrakranial hypertensjon fant man at kombinasjonen av tre eller flere MR-funn (sinusvenestenose ikke inkludert) hadde en sensitivitet på 45 % og en spesifisitet på 95 % (14). Figur 2a -d viser eksempler på typiske MR-funn assosiert med idiopatisk intrakranial hypertensjon.…”

Section: Bildediagnostikkunclassified

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