Brain Machine Interfaces for Vision Restoration: The Current State of Cortical Visual Prosthetics

Niketeghad, Soroush; Pouratian, Nader

doi:10.1007/s13311-018-0660-1

Cited by 96 publications

(60 citation statements)

References 101 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A preliminary study in one blind patient demonstrated the safety and basic functional aspects of the device. Ongoing clinical trials that started in late 2017 have so far included five blind patients with a follow-up planned for 5 years ( Niketeghad and Pouratian, 2019 ). Preliminary results indicated that patients were able to perceive phosphenes ( Barry et al, 2020 ).…”

Section: Brain Interfaces For Vision Recoverymentioning

confidence: 99%

Brain-Machine Interfaces to Assist the Blind

Ptito

Bleau

Djerourou

et al. 2021

Front. Hum. Neurosci.

View full text Add to dashboard Cite

The loss or absence of vision is probably one of the most incapacitating events that can befall a human being. The importance of vision for humans is also reflected in brain anatomy as approximately one third of the human brain is devoted to vision. It is therefore unsurprising that throughout history many attempts have been undertaken to develop devices aiming at substituting for a missing visual capacity. In this review, we present two concepts that have been prevalent over the last two decades. The first concept is sensory substitution, which refers to the use of another sensory modality to perform a task that is normally primarily sub-served by the lost sense. The second concept is cross-modal plasticity, which occurs when loss of input in one sensory modality leads to reorganization in brain representation of other sensory modalities. Both phenomena are training-dependent. We also briefly describe the history of blindness from ancient times to modernity, and then proceed to address the means that have been used to help blind individuals, with an emphasis on modern technologies, invasive (various type of surgical implants) and non-invasive devices. With the advent of brain imaging, it has become possible to peer into the neural substrates of sensory substitution and highlight the magnitude of the plastic processes that lead to a rewired brain. Finally, we will address the important question of the value and practicality of the available technologies and future directions.

show abstract

Section: Brain Interfaces For Vision Recoverymentioning

confidence: 99%

Brain-Machine Interfaces to Assist the Blind

Ptito

Bleau

Djerourou

et al. 2021

Front. Hum. Neurosci.

View full text Add to dashboard Cite

show abstract

“…[59,60] The purpose of these devices is to restore function to different organs in our body that suffered from neuronal damage whether due to an injury, disease or a physiological condition (Figure 8). Success of these devices is great and reports are increasing for more and more advanced devices that restore close to full activity of vision, [61] hearing, [62] and limbs functionality. [63] Conclusions and a Glimpse to the Future…”

Section: Interfacing With Organs and Specific Tissuesmentioning

confidence: 99%

Bioelectrochemistry and the Singularity Point “I Robot”?**

Alfonta

2021

Israel Journal of Chemistry

View full text Add to dashboard Cite

In his book “The Singularity Is Near: When Humans Transcend Biology” Ray Kurtzweil described the concept of artificial intelligence in an unorthodox way. It describes how humans will interface with machines and eventually will become one with machines. Hence, we can define a time point, which is a theoretical point when humans and machines will become one. In order to reach this point, a successful interface between the biological/organic to the inorganic matter is needed. In order for these pieces of “machinery” to communicate between one another, an exchange of matter and energy should be achieved. Electron transfer between the inorganic and organic has been the mission of bioelectrochemical systems in the past few decades. Enzymes, antibodies and nucleic acids attachment to electrodes has been achieved more than three decades ago. In the following assay I am reviewing the different advances that were made towards an integration between biological entities to inorganic ones.

show abstract

“…Focusing on pediatrics, Ibrahim and colleagues [17] address neuromodulatory strategies for the treatment of intractable epilepsy in children, including putative mechanisms of action and biomarkers for treatment success. Addressing vision restoration, Niketeghad and Pouratian [18] describe the historical thinking on cortical visual prosthetics, as well as the current state of the art, explaining the design of current devices that are either under development or in the clinical testing phase. Rabbani and colleagues [19] then complete this section by introducing us to the field of neural speech decoding using electrocorticography, exploring what a brain-computer interface for speech might entail.…”

Section: Brain-computer Interfaces For Restoring Movement Seizure Comentioning

confidence: 99%

A New Era for Surgical Neurotherapeutics

Richardson

Abel

2019

Neurotherapeutics

View full text Add to dashboard Cite

Surgical interventions now have the potential to outperform traditional drug treatments in the management of many different neurological disorders. For example, in epilepsy, despite the introduction of more than a dozen new anti-epileptic medications over the past two decades, the overall rates of seizure freedom are unchanged [1,2], whereas responsive neurostimulation is now known to confer significant improvements in seizure reduction and quality of life in these same medically refractory patients [3,4]. Thus, modern neurosurgical techniques and devices, having low morbidity and, in many cases, excellent efficacy, are increasingly seen as part of a normal spectrum of treatment that includes medications, rather than existing in a separate dimension. In this issue of Neurotherapeutics, an international group of expert authors describe this new era for therapies delivered via neurosurgery, in which advances in neuroscience, computational biology, and imaging are driving both the evolution of traditional strategies and the initiation of novel approaches.

show abstract

Brain Machine Interfaces for Vision Restoration: The Current State of Cortical Visual Prosthetics

Cited by 96 publications

References 101 publications

Brain-Machine Interfaces to Assist the Blind

Brain-Machine Interfaces to Assist the Blind

Bioelectrochemistry and the Singularity Point “I Robot”?**

A New Era for Surgical Neurotherapeutics

Contact Info

Product

Resources

About