Brain potential amplitude varies as a function of Borna disease virus-specific immune complexes in obsessive–compulsive disorder

Is blood transfusion safe? BDV and neuropsychiatric illness

“…This has also been reported in research reports (5,6). Treatment with Amantadine in obsessive-compulsive patients shows that there were variations in brain potential amplitudes with respect to BDV specific immune complexes (7). Thus the possibility of BDV-inducing neuropsychiatric illness cannot be rejected.…”

“What's Bugging the Gut in Ocd?” a Review of the Gut Microbiome in Obsessive-Compulsive Disorder

“…[75] In addition to group Aβ-hemolytic streptococcal infection, other infectious diseases may be involved in the development of OCD. Some studies have associated OCD with infections with borna virus disease [76] and toxoplasma gondii. [77] These observations hint to the possible connection between the immune system and the development of OCD, leading to the progression of studies to assess immune parameters in OCD.…”

Searching for the Immune Basis of Obsessive-Compulsive Disorder

“…In the early 1990's Borna disease virus was associated with psychiatric disorders, mainly mood disorders. Dietrich et al [38] reported an association between Borna disease virus-specific circulating immune complexes and dysfunction in the cingulate cortex of OCD patients submitted to a mental flexibility test. It was suggested that Borna disease virus-induced immune response would be responsible for enhanced levels of glutamate, leading to thalamocortical dysfunction [39].…”