Brain Tumor in Newborn Babies

Takaku, Akira; Kodama, Namio; Ohara, H; Hori, Shigeaki

doi:10.1159/000119793

Cited by 53 publications

(28 citation statements)

References 9 publications

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“…Brain stem tumors were not observed in our study and accord ing to the literature, they are rare in this age group [8][9][10]16], There were no tumors located in the cerebellopontine angle: in other studies on infants, this location was an exception [8,16].…”

Section: Brain Tumors In Infancysupporting

confidence: 84%

Brain Tumors in the First Two Years of Life: A Review of Forty Cases

et al. 1993

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From 1962 to 1989, 40 infants with brain tumors and less than 2 years old were treated at the Department of Neurology of the Clinical Hospital of the University of São Paulo Medical School. The clinical and neuropathological findings were reviewed as to histological diagnosis, age, sex, signs and symptoms, therapy and outcome. Medulloblastoma was the most common histological type (n = 11), followed by ependymoma (n = 9), choroid plexus tumor (n = 6), astrocytoma (n = 3) and primitive neuroectodermal tumor (n = 2). The tumor was infratentorial in 21 infants, supratentorial in 18 and disseminated in 1.

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Section: Brain Tumors In Infancysupporting

confidence: 84%

Brain Tumors in the First Two Years of Life: A Review of Forty Cases

et al. 1993

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“…Our statistics show that medulloblastoma and benign astrocytoma are the most common, with choroid plexus papilloma and meningeal sarcoma ranking third and fourth. Takaku et al [32] report teratoma as the most common tumor in the neonatal period.…”

Section: Discussionmentioning

confidence: 99%

“…One is advised to separate, however, neonatal brain tumors from those diagnosed in later infancy, since the former have poorer prognosis: only 4 out of 14 neonates reported by Takaku et al [32] survived more than 1 year after surgery. The opposite is true for tumors occurring during the second 6 months of life.…”

Section: Discussionmentioning

confidence: 99%

“…11 chil dren with normal head size were found to have hydrocephalus. The most common signs were a full, bulging fontanelle and rapid increase in head circumference, expressive of a flexible skull and open sutures [9,26,31,32], Despite this increase in intracranial pressure (ICP) the incidence of papilledema (28%) was low. Other signs of increased ICP were vomiting, abducens palsy, lethargy, irritability.…”

Section: Signs and Symptoms (Table 11-iv)mentioning

confidence: 99%

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Brain Tumors during the First Year of Life

Raimondi

Tomita²

1983

Pediatr Neurosurg

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Among 341 childhood brain tumors treated at Northwestern University – Children’s Memorial Hospital during the years 1967–1980, there were 39 children (11%) who presented during the first year of life. Half of the total number of childhood choroid plexus papillomas, meningeal sarcomas and teratomas we treated occurred in this particular age group. Supratentorial tumors were more common than infratentorial, a rate of 1.8:1. Medulloblastoma and benign astrocytoma were the most common histological types. Hydrocephalus was present in 82% of the children and papilledema in 28%, so that progressive enlargement of head circumference was the most common reason for referral. For the 37 patients who underwent surgical removal or biopsy of the tumor, the 1-month mortality rate was 19% and the 1-, 3- and 5- year survival rates were 46, 30 and 22%, respectively. Whenever tolerated, roentgen therapy was given. Most of the 24 deaths occurred within 6 months of the time of diagnosis. 5 patients (1 each with malignant astrocytoma, medulloblastoma, meningeal sarcoma, and 2 with choroid plexus papilloma) are still alive 5 years later, without neurological or mental deficit, and with no sign of recurrence. There were three exceptions to Collin’s rule. Among the 15 survivors, 5 suffer mental retardation.

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“…The out come of neonates and infants after resection of postnatally diagnosed intracranial teratomas, in general, has been poor. A survival of 8 months [13], 18 months [ 14], 2 years [15] and 7 years, 9 months [16] has been reported. In a recent review of 45 cases of neonatal brain tumors, 12 were teratomas; this tumor type was the most lethal, with a mean survival of 21 days [3].…”

Section: Discussionmentioning

confidence: 99%

Prenatal Diagnosis of Intracranial Teratoma

et al. 1993

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We are reporting a case of an infant with an intracranial malignant teratoma which was diagnosed prenatally by ultrasound at 37 weeks of gestational age. After a cesarean delivery, the resection of the tumor was performed at 24 h of age. This infant is currently the oldest reported survivor that carries this prenatal diagnosis. He is also the first reported infant with surgical intervention for an intracranial malignant teratoma diagnosed prenatally.

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Brain Tumor in Newborn Babies

Cited by 53 publications

References 9 publications

Brain Tumors in the First Two Years of Life: A Review of Forty Cases

Brain Tumors in the First Two Years of Life: A Review of Forty Cases

Brain Tumors during the First Year of Life

Prenatal Diagnosis of Intracranial Teratoma

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