Branch Retinal Arterial Occlusion Treated With Intravenous Prostaglandin E1 and Steroids

Steigerwalt, Robert D; Belcaro, Gianni; Cesarone, M. R.; Angelis, Mauro De; Florio, Francesca Romana; Gattegna, Roberto; Pascarella, Antonella

doi:10.1097/icb.0b013e3182051de9

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…The authors normally use i.v. PGE1 for acute ocular ischemia (3)(4)(5)(6) and would have preferred that here. With i.v.…”

Section: Discussionmentioning

confidence: 99%

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Visual improvement in a patient with paracentral acute middle maculopathy treated with prostaglandin E1

Steigerwalt¹,

Nebbioso

2020

DD&T

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paracentral acute middle maculopathy, acute retinal ischemia, prostaglandin E1 The authors present the use of prostaglandin E1 (PGE1) for the treatment of an acute paracentral acute middle maculopathy (PAMM). A 78-year-old white female was seen with a sudden loss of vision in her left eye (OS) to 20/200 noted upon awakening. The right eye (OD) saw 20/20. A complete eye exam was done and an ocular coherent tomography revealed retinal thickening and a whitening of the inner nuclear layer in the area of the macula OS. A diagnosis of PAMM in the OS was made. Treatment was immediately started with 70 μg of PGE1 administered over 1.5 hours in the form of a skin cream. A volume of 3.5 cc of skin cream was applied in divided doses to the inner surface of the forearm, rubbed into the skin and allowed to dry. The same 70 μg of PGE1 in 3.5 cc of skin cream was repeated once the next morning. The patient began to see better the second day of treatment with a final visual acuity of 20/20. The OD was unchanged. After 14 months she was stable with no further treatment. PAMM is an ischemic process of the inner retina. PGE1, a potent vasodilator of the microcirculation, when given immediately seemed to be useful in restoring vision in this form of retinal ischemia. Treatment was immediately started with PGE1 in the form of a skin cream with visual improvement. The authors normally use PGE1 intravenously for acute ocular ischemia and would have preferred that here. Intravenous PGE1 was not available and was substituted with the skin cream of PGE1 that worked well for the patient.

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“…The authors normally use i.v. PGE1 for acute ocular ischemia (3)(4)(5)(6) and would have preferred that here. With i.v.…”

Section: Discussionmentioning

confidence: 99%

“…PGE1 with steroids was shown to improve the visual acuity as well as the ocular and retrobulbar blood flow. An acute branch retinal arterial occlusion has also been successfully treated (6). In this case report PGE1 was not immediately available for i.v.…”

Section: Introductionmentioning

confidence: 98%

Visual improvement in a patient with paracentral acute middle maculopathy treated with prostaglandin E1

Steigerwalt¹,

Nebbioso

2020

DD&T

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Pycnogenol® improves cochlear-vestibular microcirculatory dysfunction, and associated symptoms

BELCARO,

CESARONE,

SCIPIONE

et al. 2024

Otorhinolaryngology

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Branch Retinal Arterial Occlusion Treated With Intravenous Prostaglandin E1 and Steroids

Abstract: Immediate prostaglandin E1 IV and steroids should be considered in cases of recent-onset branch retinal arterial occlusion to restore retinal blood flow and improve visual acuity.

Cited by 2 publications

References 9 publications

Visual improvement in a patient with paracentral acute middle maculopathy treated with prostaglandin E1

Visual improvement in a patient with paracentral acute middle maculopathy treated with prostaglandin E1

Pycnogenol® improves cochlear-vestibular microcirculatory dysfunction, and associated symptoms

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