Breast Cancer: A Paradigm Shift

Abstract

Breast cancer cases are surging across the globe. The incidence of breast cancer increased in all regions of the world at an annual rate of 3.1% over a period of 1980e2001. The maiden global analysis that factored in the trend over the past three decades shows the number of new breast cancer cases diagnosed worldwide has increased dramatically from about 6.4 lakhs in 1980 to 16 lakhs in 2010. On the contrary, the rise in deaths from breast cancer globally has been slower, increasing from about 2.5 lakhs in 1980 to 4.25 lakhs in 2010, possibly reflecting the effectiveness of early detection and advances in treatment in developed countries. However, the disease still killed 2 lakhs women around the world in 2010dand 46,000 of them were of reproductive age in developing countries. The study published in the British medical journal says that 51% of these new cases of breast cancer occurred in developing countries like India.

Computational Screening and Molecular Dynamic Simulation of Breast Cancer Associated Deleterious Non-Synonymous Single Nucleotide Polymorphisms in TP53 Gene

“…One of the common malignancies and leading causes of cancer death faced by women around the world is breast cancer. Globally, the death rate of breast cancer has been rising around 2.5 lakhs in 1980 to 4.25 lakhs in 2010 [1] . Even in countries like China and India, its incidence is increased around 30% over the last decade whereas in Japan, Korea and Singapore it was doubled or even tripled [2] .…”

Prediction and Analysis of Ligands against Estrogen Related Receptor Alpha

“…Global rise in deaths from breast cancer has been rising from about 2.5 lakhs in 1980 to 4.25 lakhs in 2010 (Choudhrya et al, 2012). Its incidence rate is high in developed regions and is low in most of the developing regions of the world (Curado, 2011).…”