Breast Cancer in a Man With Human Immunodeficiency Virus Infection

Widrick, Patrick; Boguniewicz, Ann; Remick, S. C.

doi:10.1016/s0025-6196(11)63597-0

Cited by 14 publications

(9 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Early in the HIV epidemic many authors perceived that BC, in the setting of HIV infection, tends to occur at a relatively early age, usually with increased bilateral disease, unusual histology and early metastatic spread, resulting in a poor outcome and early relapse . 10,19,36,41,83,84 Over time, as more data appeared in the literature, this statement has been refuted. 85,73 In their updated case series from Harlem, New York, Sarhan and Oluwole demonstrated that the cancer stage, pathological cancer characteristics and survival outcome was similar in HIV-positive and HIV-negative patients.…”

Section: Clinical and Pathological Characteristics Of Bc In Plwhamentioning

confidence: 99%

“…The evidence presented will be interpreted in the context of three historical time frames: pre-HAART, early HAART and HAART. While BC does occur in men living with HIV/AIDS (MLWHA), 10 this review will mainly focus on BC in women living with HIV/AIDS (WLWHA). Kaposi’s sarcoma (KS) and non-Hodgkin’s lymphoma (NHL) that may also have localized to the breast in PLWHA, 11-13 falls outside the scope of this review.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Breast cancer, human immunodeficiency virus and highly active antiretroviral treatment; implications for a high-rate seropositive region

Chirkut¹

2019

Oncol Rev

View full text Add to dashboard Cite

Sub-Saharan Africa is the region in the world with the most people infected with the human immunodeficiency virus (HIV). The incidence of breast cancer is also rising in the region. This transcript focusses on the burden of these two diseases when they converge in the same populace. This comprehensive literature review of the topic suggests a trend towards an increasing incidence of breast cancer in the HIV-infected population, and the rationale for such a tendency is hypothesized, especially in the context of the availability of highly active antiretroviral therapy. Besides the age at diagnosis, all other clinical characteristics appear to be similar in HIV-positive and HIV-negative breast cancer populations. Outcomes of the different treatment modalities for breast cancer in HIV-positive patients are also appraised and finally innovative areas of future research are suggested along with plausible recommendations.

show abstract

Section: Clinical and Pathological Characteristics Of Bc In Plwhamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Breast cancer, human immunodeficiency virus and highly active antiretroviral treatment; implications for a high-rate seropositive region

Chirkut¹

2019

Oncol Rev

View full text Add to dashboard Cite

show abstract

“…While there are various reports on the poor response of HIV-positive women to chemotherapy, reports of radiation toxicity could not be identified 82-84 . Radiation has been reported to be well tolerated in patients treated to 64.8 and 65Gy 85,86 . There is insufficient evidence to recommend any treatment modifications of HIV-positive women with breast cancer.…”

Section: Radiosensitivity In Tumors Common To the General Populationmentioning

confidence: 99%

Radiotherapy for patients with the human immunodeficiency virus: Are special precautions necessary?

Housri

Yarchoan

Kaushal

2009

Cancer

View full text Add to dashboard Cite

Shortly after the onset of the AIDS epidemic in the 1980s, reports of radiation-associated toxicity in HIV and AIDS patients began to appear in the medical literature. While most reports have focused on AIDS-defining malignancies such as Kaposi's sarcoma, greater than expected toxicity following a course of radiotherapy or chemoradiotherapy has also been documented in cancers not generally classified as HIV-related. With improved antiretroviral therapies, HIV patients are living longer and have the potential to develop a variety of HIV associated and non-associated malignancies that require treatment, including radiation therapy. This review reports the published data on the interactions of HIV, AIDS, and antiretroviral therapy with radiation and the implications for the management of malignancies in HIV patients.

show abstract

“…Plasmacytoma and Kaposi sarcoma have recently been reported to present as breast masses or breast enlargement in HIV-infected individuals [16,17]. Multiple cases of breast carcinoma in HIV-infected patients (most of whom were women [18][19][20]; less often, they were men [21,22]) have also been described. These cases have spurred some debate about whether a relationship exists between breast cancer and HIV infection, although no definite link has ever been demonstrated.…”

Section: Discussionmentioning

confidence: 99%

“…Because breast carcinoma is rare in male patients [15], most cases of breast enlargement in HIV-infected patients have been presumed to be benign. However, there have been recent reports of various malignancies presenting in the breasts of HIV-infected men, including Kaposi sarcoma [16], plasmacytoma [17], and carcinoma [18][19][20][21][22]. In addition, non-Hodgkin lymphoma (NHL) may rarely present as a breast mass [23], although this has not been reported specifically in an HIV-infected individual.…”

mentioning

confidence: 99%

Breast Enlargement in 13 Men Who Were Seropositive for Human Immunodeficiency Virus

et al. 2002

View full text Add to dashboard Cite

Breast enlargement, a condition that was rarely reported in the era before highly active antiretroviral therapy, is emerging as a problem in the treatment of male human immunodeficiency virus (HIV)-infected patients. Evaluation of this condition must distinguish between gynecomastia (proliferation of ducts and periductal stroma), lipomastia (adipose-tissue deposition), and malignancy. We describe 13 HIV-infected men, all of whom had exposure to antiretroviral therapy, who presented with breast enlargement. Nine of these patients had gynecomastia, only 1 had lipomastia, and 3 had lymphoma (2 had non-Hodgkin lymphoma and 1 had Hodgkin disease). Gynecomastia was unilateral in all but a single case. In addition, all but 1 of our patients with gynecomastia had prolonged exposure to protease inhibitors. Six patients had potential causes of gynecomastia other than antiretroviral therapy, including liver disease (in 2 patients), mild hypogonadism (in 1), long-term marijuana use (in 2), and use of medications that have known associations with gynecomastia (in 3). Although most causes of breast enlargement in HIV-infected men are likely to be benign, malignancies other than carcinoma are of concern.

show abstract

Breast Cancer in a Man With Human Immunodeficiency Virus Infection

Cited by 14 publications

References 14 publications

Breast cancer, human immunodeficiency virus and highly active antiretroviral treatment; implications for a high-rate seropositive region

Breast cancer, human immunodeficiency virus and highly active antiretroviral treatment; implications for a high-rate seropositive region

Radiotherapy for patients with the human immunodeficiency virus: Are special precautions necessary?

Breast Enlargement in 13 Men Who Were Seropositive for Human Immunodeficiency Virus

Contact Info

Product

Resources

About