Breast Cancer in Vivo: Contrast Enhancement with Thermoacoustic CT at 434 MHz—Feasibility Study

Kruger, Robert A.; Miller, Kathy D.; Reynolds, Handel E.; Kiser, William L.; Reinecke, Daniel R.; Kruger, Gabe A.

doi:10.1148/radiology.216.1.r00jl30279

Cited by 251 publications

(180 citation statements)

References 24 publications

Supporting

Mentioning

180

Contrasting

Order By: Relevance

“…We denote by P the operator which takes smooth initial data with support in B to the solution of (1), (10) restricted to S × [0, ∞) and by W the operator taking f to the solution of (1), (2) restricted to S × [0, ∞). These operators are simply related by W = ∂ t P. An explicit representation for P comes from the well-known formula [4] …”

Section: Introduction and Statement Of Resultsmentioning

confidence: 99%

Inversion of Spherical Means and the Wave Equation in Even Dimensions

Finch¹,

Haltmeier²,

Patch³

2007

SIAM J. Appl. Math.

224

317

View full text Add to dashboard Cite

We establish inversion formulas of the so called filtered back-projection type to recover a function supported in the ball in even dimensions from its spherical means over spheres centered on the boundary of the ball. We also find several formulas to recover initial data of the from (f, 0) (or (0, g)) for the free space wave equation in even dimensions from the trace of the solution on the boundary of the ball, provided the initial data has support in the ball.

show abstract

Section: Introduction and Statement Of Resultsmentioning

confidence: 99%

Inversion of Spherical Means and the Wave Equation in Even Dimensions

Finch¹,

Haltmeier²,

Patch³

2007

SIAM J. Appl. Math.

224

317

View full text Add to dashboard Cite

show abstract

“…In recent years, various thermo-acoustic imaging (TAI) demonstrations have been reported [11][12][13]. Two-and three-dimensional (2-D and 3-D) imaging of breast tissue phantoms or real breast tissue specimens have been investigated [14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

An Integrated Simulation Approach and Experimental Research on Microwave Induced Thermo-Acoustic Tomography System

Song¹,

Zhao²,

Wang³

et al. 2013

PIER

View full text Add to dashboard Cite

Abstract-Microwave induced thermo-acoustic tomography (MI-TAT) has great potential in early breast cancer detection because it utilizes the advantages of both microwave imaging and ultrasound imaging. In this paper, a fast and efficient simulation approach based on a hybrid method which combines finite integration time domain (FITD) method and pseudo-spectral time domain (PSTD) method is developed. By using this approach, energy deposition of biology tissue illuminated by electromagnetic fields can be accurately simulated. Meanwhile, acoustic properties of the tissue can be efficiently simulated as well. Based on this approach, a MITAT model is created and some simulated results are analyzed. Furthermore, some real breast tissues are adopted to perform the thermo-acoustic imaging experiment. Comparisons between experimental and simulated results are made. The feasibility and effectiveness of the proposed approach are demonstrated by both numerical simulations and experimental results.

show abstract

“…Three alternative active microwave imaging techniques are under development, Hybrid Microwave-Induced Acoustic imaging [2][3][4], Microwave Tomography [5][6][7][8][9][10] and Ultra-Wideband (UWB) Radar imaging [11][12][13][14][15][16][17][18][19][20][21].…”

Section: Introductionmentioning

confidence: 99%

Channel-Ranked Beamformer for the Early Detection of Breast Cancer

O’Halloran¹,

Glavin²,

Jones³

2010

PIER

View full text Add to dashboard Cite

Abstract-Confocal Microwave Imaging (CMI) for the early detection of breast cancer is based on several assumptions regarding the dielectric properties of normal and malignant breast tissue. One of these assumptions is that the breast is primarily dielectrically homogeneous, and that the propagation, attenuation and phase characteristics of normal breast tissue allows for the constructive addition of the Ultra Wideband (UWB) returns from dielectric scatterers within the breast. However, recent studies by Lazebnik et al. have highlighted a very significant dielectric contrast between normal adipose and fibroglandular tissue within the breast. This dielectric heterogeneity presents a considerably more challenging imaging scenario, where constructive addition of the UWB returns, and therefore tumor detection, is much more difficult. In a dielectrically homogeneous breast, each additional beamformed backscattered signal adds coherently with existing signals, resulting in an improved image of any dielectric scatterers present. However, in a dielectrically heterogeneous breast, signals with a longer propagation distance are more likely to encounter heterogeneity and therefore are more prone to incoherent addition, reducing the overall quality of the breast image. In this paper, a novel beamforming algorithm is described, which gives extra weighting to signals with shorter propagation distances to create an improved image of the breast. The beamformer is shown to provide improved images of more dielectrically heterogeneous breasts than the traditional delay and sum beamformer from which it is derived.Corresponding author: M. O'Halloran (martin.ohalloran@gmail.com). † All the authors are also with

show abstract

Breast Cancer in Vivo: Contrast Enhancement with Thermoacoustic CT at 434 MHz—Feasibility Study

Cited by 251 publications

References 24 publications

Inversion of Spherical Means and the Wave Equation in Even Dimensions

Inversion of Spherical Means and the Wave Equation in Even Dimensions

An Integrated Simulation Approach and Experimental Research on Microwave Induced Thermo-Acoustic Tomography System

Channel-Ranked Beamformer for the Early Detection of Breast Cancer

Contact Info

Product

Resources

About