Breast Cancer Metastases to the Pancreas

Abstract

We present two patients with breast cancer metastases to their pancreas and review their workup and clinical management in light of our experience and the existing published literature. We propose that metastatic disease to the pancreas has to remain in the differential diagnosis for any patient with a new pancreatic mass and prior cancer history. Surgical resection is a viable treatment option for patients with isolated metastatic disease to the pancreas if the underlying biology of the metastatic tumor is favorable.

Pancreatic metastasis from malignant phyllodes tumor of the breast

“…However, several unusual metastatic sites, including duodenum, brain, nasal cavity, skin, oral cavity, skeletal muscle, mandible, and maxilla, have also been reported [11][12][13]. Metastasis to pancreas is rare, and only a few cases have been reported [5][6][7][8][9][10].…”

Dermatofibrosarcoma metastases to the pancreas: A case report

“…A Whipple's procedure and distal pancreatectomy with splenectomy were performed. Unlike pancreatic metastases from breast cancer[10], aggressive surgery for a resectable fibrosarcoma of the pancreas was indicated[11,12]. Debulking surgery prolongs long-term survival and controls local recurrence.…”

Solitary pancreatic metastasis from breast cancer

“…Описано всего 26 случаев в период с 1980 по 2017 г. [5,[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26]. Чаще всего солитарные метастазы были выявлены в головке ПЖ.…”