2022
DOI: 10.3389/fpsyg.2022.861198
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Breast Cancer Survivors’ Lived Experience of Adjuvant Hormone Therapy: A Thematic Analysis of Medication Side Effects and Their Impact on Adherence

Abstract: ObjectivesSide effects from Hormone Therapy (HT) impact medication adherence in breast cancer survivors. Understanding the most distressing HT side effects and their impacts may inform the development and implementation of interventions to alleviate these side effects and maximise HT adherence. This study aimed to explore the lived experience of adjuvant HT and understand the impact of HT side effects on adherence in a sample of breast cancer survivors.MethodsTwenty-five female breast cancer survivors who were… Show more

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Cited by 13 publications
(26 citation statements)
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“…The aim of this review was to investigate the effects of exercise interventions on CRF and sleep disturbances in women with breast cancer who are receiving HT, in order to provide more clarity on the most appropriate exercise recommendations for reducing side effects of HT. Despite the importance of HT for reducing cancer recurrence, adherence remains sub‐optimal due to the impact of adverse side effects 14 . Some of the most common side effects experienced by breast cancer survivors include CRF and sleep disturbances 15 .…”
Section: Discussionmentioning
confidence: 99%
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“…The aim of this review was to investigate the effects of exercise interventions on CRF and sleep disturbances in women with breast cancer who are receiving HT, in order to provide more clarity on the most appropriate exercise recommendations for reducing side effects of HT. Despite the importance of HT for reducing cancer recurrence, adherence remains sub‐optimal due to the impact of adverse side effects 14 . Some of the most common side effects experienced by breast cancer survivors include CRF and sleep disturbances 15 .…”
Section: Discussionmentioning
confidence: 99%
“…Poor adherence is often attributed to the adverse side effects associated with HT 13 . The most reported side effects include fatigue, sleep disturbances, hot flashes and joint pain 14,15 …”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…The domain of side effects represented an essential impact on treatment satisfaction and adherence. Adverse effects from hormonal therapy were considered the main barrier to nonadherence [ 28 , 34 36 ], and it negatively impacts the quality of life [ 32 ]. In our study, the highest beta coefficient was for the variable side effects.…”
Section: Discussionmentioning
confidence: 99%
“…Long-term therapy of at least 5 years, and even up to 10 years in high-risk groups, is therefore an essential part of adjuvant breast cancer tumor therapy. Next to the medication side effects, such as sleep disorders, hot flashes, pain and anxiety, as well as a reduced quality of life, this has an impact on therapy adherence [ 38 ]. However, the CNS side effects also show that these substances must affect the brain and therefore can pass through or affect the BBB.…”
Section: Breast Cancermentioning
confidence: 99%