Breast Cytology and Pathology in Pregnancy and Lactation

Soleimani, Vahid; Jahanbin, Behnaz

doi:10.1007/978-3-030-41596-9_4

Cited by 3 publications

(2 citation statements)

References 15 publications

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“…[ 4 5 6 7 ] Pregnancy and lactation with certain therapies can also cause infarction of breast lesions. [ 8 ] Anticoagulants such as warfarin lead to infarction and fat necrosis-like features in predisposed individuals. [ 9 10 ] Infarction is also seen after an episode of trauma in fibroadenoma.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Infarcted Breast Lesions on FNAC, a Blustering Fool: Short Case Series

Chaudhari,

Meshram,

Bhatkule

et al. 2023

Journal of Cytology

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Introduction: Fine-needle aspiration cytology (FNAC) is often used as a screening tool. Cytopathologist should be aware of various mimickers of the malignancy. One of these is infarction of benign breast lesions. Careful examination of cytomorphological features will avoid the misdiagnosis of malignancy in such cases. Material and Methods: Six cases were diagnosed as benign breast lesion for 4 years and 5 months in our newly established tertiary referral center. Histopathology follow-up was available in one case. Results: Of six cases, three cases (50%) were reported as fibroadenoma with infarction, two cases (33%) as benign breast lesion with infarction favor fibroadenoma, and one as breast lesion with infarction favor phyllodes tumor in view of recurrence. Most were in the second or third decade of their life. All cases showed dyscohesive cells with pyknotic nuclei. Monolayered sheets of necrotic cells were seen in the four cases (66%). Viable cells were seen in four cases. Conclusions: FNAC provides a rapid and accurate diagnosis of benign breast lesions with infarction in the hands of experienced pathologists who can help in better patient care. Small-sized uniform pyknotic nuclei of dyscohesive cells and regular nuclear membranes help to differentiate them from inflammatory and malignant lesions.

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Section: Discussionmentioning

confidence: 99%

Diagnosis of Infarcted Breast Lesions on FNAC, a Blustering Fool: Short Case Series

Chaudhari,

Meshram,

Bhatkule

et al. 2023

Journal of Cytology

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“…A thorough physical examination may quickly differentiate conditions such as trauma, broken nipple, and mastitis. The most common cause of pathological nipple discharge is ductal papilloma, which accounts for 35–57% of cases, followed by duct ectasia (17–36%) and malignant lesions (4–21%) [ 28 , 29 ]. Pregnancy-associated breast cancer (PABC) is defined as breast cancer diagnosed during pregnancy or in the first year of lactation.…”

Section: Discussionmentioning

confidence: 99%

Rusty pipe syndrome: a case report and review of the literature

Tang

Zhu

Chen

et al. 2022

BMC Pregnancy Childbirth

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Background Painless bloody nipple discharge is often classified as pathological due to its association with malignant lesions. However, it can also be a completely harmless condition. Rusty pipe syndrome is a rare cause of benign, self-limiting bloody nipple discharge during late pregnancy and early lactation. Given that rusty pipe syndrome is not described in conventional textbooks, we thought it would be appropriate to bring this benign disease to the notice of readers. Case presentation A 31-year-old G1P1 female delivered an infant with a birth weight of 3000 g via cesarean section at 39 weeks of gestation. The baby was admitted to the pediatric intensive care unit for a suspected oblique inguinal hernia. The mother had bilateral painless bloody nipple discharge when she started to express milk. A physical examination uncovered no signs of inflammation, engorgement, palpable mass, tenderness, cracks or ulcers. A breast ultrasound and cytological analysis revealed no signs of a neoplasm. Without any medical intervention, the color of the rusty milk changed from dark brown to light brown during hospitalization and finally resolved six days postpartum. Conclusion Rusty pipe syndrome is a self-limiting benign condition that should be considered in the differential diagnosis of bloody nipple discharge. Awareness of this rare disease by medical professionals would be extremely beneficial for avoiding unneeded examinations and discontinuity of exclusive breastfeeding.

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