2017
DOI: 10.1002/mp.12279
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Breast-density measurement using photon-counting spectral mammography

Abstract: Purpose: To evaluate a method for measuring breast density using photon-counting spectral mammography. Breast density is an indicator of breast cancer risk and diagnostic accuracy in mammography, and can be used as input to personalized screening, treatment monitoring and dose estimation. Methods: The measurement method employs the spectral difference in x-ray attenuation between adipose and fibro-glandular tissue, and does not rely on any a priori information. The method was evaluated using phantom measuremen… Show more

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Cited by 17 publications
(19 citation statements)
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References 57 publications
(120 reference statements)
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“…Spectral mammography with energy-resolved photon counting detectors eliminates the need for two exposures, reducing radiation dose. A recent comparative study using BIRADS, Cumulus, a fuzzy C-means segmentation and spectral mammography material decomposition showed excellent right-left correlation for the latter, with much higher precision than for the other techniques (142), an observation replicated in a recent study from Sweden (143).…”
Section: Spectral Mammographymentioning
confidence: 70%
“…Spectral mammography with energy-resolved photon counting detectors eliminates the need for two exposures, reducing radiation dose. A recent comparative study using BIRADS, Cumulus, a fuzzy C-means segmentation and spectral mammography material decomposition showed excellent right-left correlation for the latter, with much higher precision than for the other techniques (142), an observation replicated in a recent study from Sweden (143).…”
Section: Spectral Mammographymentioning
confidence: 70%
“…Spectroscopic x‐ray imaging detectors are under development in academic and industry laboratories. Advantages of spectroscopic detectors over energy‐integrating detectors include improved dose efficiency and the potential for single‐exposure, material‐specific imaging …”
Section: Introductionmentioning
confidence: 99%
“…The highest-occurrence (25.9 %) breast corresponds to an average compression thickness of 7 cm and a glandular density of 18.1 %. The breast density values were calculated with the built-in breast-density measurement tool in the Philips system, for which the spectral image data was decomposed into volumes of glandular and adipose tissue by calibration on tissue-equivalent material [30][31][32]. The attenuation coefficient of this target breast was calculated using the XCOM photon cross section database of the National Institute of Standards and Technology (NIST) [33], utilizing the breast adipose and glandular tissue compositions defined by the International Commission on Radiation Units and Measurements (ICRU) in report 46.…”
Section: Optimization Proceduresmentioning
confidence: 99%