Breast hamartoma: A Case Report

Gatti, Giovanna; Mazzarol, Giovanni; Simsek, Serife; Viale, Giuseppe; Peradze, Nickolas; Luini, Alberto

doi:10.1007/s10549-004-1097-2

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…However, PASH foci were described as a common finding in breast hamartomas. In addition, the majority of hamartomas contain fatty tissue (18, 19). Despite thorough examination of the specimens we did not find adipose tissue components; we therefore consider that our case is a pure nodular form of PASH.…”

Section: Discussionmentioning

confidence: 99%

Rapidly growing nodular pseudoangiomatous stromal hyperplasia of the breast in an 18‐year‐old girl

Žúbor

Kajo

Ca³

et al. 2006

APMIS

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Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a rare benign proliferation of mesenchymal stromal cells with irregular slit-like formations resembling angiomatous structures. In the majority of cases this lesion is a focal microscopic finding in breast biopsies performed for benign or malignant diseases. It may present in a pure diffuse or nodular form. The exact etiology and pathogenesis of this tumor-like lesion is still unknown, but a proliferative response of myofibroblasts to hormonal stimuli has been postulated. A large 12 x 9 x 3.5 cm rapidly growing nodular form of PASH of the breast in an 18-year-old woman is here described with clinical and histological findings. A possible hormonal etiology was indicated by elevated progesterone (three-fold) and decreased estrogen serum levels. Different diagnostic lesions, such as giant fibroadenoma and low-grade angiosarcoma, are discussed. To the authors' knowledge this is only the fourth case of nodular PASH of the breast reported in the English literature.

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Section: Discussionmentioning

confidence: 99%

Rapidly growing nodular pseudoangiomatous stromal hyperplasia of the breast in an 18‐year‐old girl

Žúbor

Kajo

Ca³

et al. 2006

APMIS

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“…Benign tumor of the breast contains a variable amount of adipose, glandular, and fibrous tissue, so it sometime called fibroadenolipoma and lipofibroadenoma or adenolipoma [26]. It is an uncommon benign tumor that present as palpable well encapsulated, discrete painless lump of unknown etiology, may be due to dysgensis rather than complete tumor process in addition; some case linked to a genetic defect named Cowden's disease [24].…”

Section: Hamartomamentioning

confidence: 99%

Breast lumps: Types, biomarkers and prognosis

Hameed¹,

Noel²,

Ajeel³

2022

GSC Adv. Res. Rev.

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Introduction: The breast is a dynamic organ in the female and the symptoms related to it considered a major cause enrolled the women to get medical intension, a complete physical, radiological, and cytological examination should be accomplished until the symptoms resolved or benign\ malignant condition established, there were many types of benign tumor in the breast: solid or cystic, painless or painful with different ways for management either by close surveillance or by surgical removal. But the breast cancer required hard work to establish the histological and pathological grade. Conclusion: to treat the breast cancer properly the cancer should stratify into molecular entities by using hormonal biomarker (ER, PR) and using of oncoprotein HER2 and proliferating index Ki-67, usage of these markers is satisfying for grouping the breast cancer subtypes into four major entities which are Luminal A, Luminal B, HER2+, and triple negative tumor.

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Breast hamartoma: A Case Report

Cited by 2 publications

References 2 publications

Rapidly growing nodular pseudoangiomatous stromal hyperplasia of the breast in an 18‐year‐old girl

Rapidly growing nodular pseudoangiomatous stromal hyperplasia of the breast in an 18‐year‐old girl

Breast lumps: Types, biomarkers and prognosis

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