Breast tuberculosis, a rare entity

Shrestha, Abha; Gautam, Keyoor; Pyakurel, Devish; Pradhan, Santosh; Pant, Vivek

doi:10.1016/j.idcr.2019.e00530

Cited by 9 publications

(12 citation statements)

References 6 publications

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“…Previous studies have shown that the females between the ages of 20-40 years are more effected by TM. 11 Shrestha et al 12 has also reported similar findings stating that tuberculous mastitis is common in females of reproductive age group and rare in males. In another Indian frequency report, Tiwari et al 13 reported 1.77% of tuberculous mastitis cases where 50% were in third decade of life.…”

Section: Discussionmentioning

confidence: 71%

Tuberculous Mastitis in Females of South Punjab: A Clinicopathological Analysis of Ten Years from Pakistan

Samad¹,

Bukhar²,

Sartaj³

et al. 2020

BIOMEDICA

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Background and Objective: Extrapulmonary tuberculosis occurring in breast is a rare disorder in West but is still present in developing nations where tuberculosis is endemic. Tuberculous Mastitis (TM) is difficult to diagnose as it has vague clinical symptoms and insufficient radiological findings. The objective of this study was to determine the frequency of tuberculous mastitis by accessible modalities for early diagnosis. Methods: After the Institutional Ethical Board approvals, Pathology laboratory archives and medical records of 5000 patients from Ibn-e-Sina Hospital Research Institute, Multan and Multi Test Laboratory, were retrieved from the year 2008 to 2018. A retrospective analysis of fine needle aspiration cytology (FNAC) results of patients who presented with breast lumps was carried out. The interpretation of cytological findings and Ziehl Neelsen stained smears was carried out by cytopathologists and microbiologists respectively. Mycobacterium DNA was detected using polymerase chain reaction (PCR) in selected cases. Results: Out of 5000 patients, tuberculosis was diagnosed in 264 (5.28%) cases on FNAC. Acid fast bacilli (AFB) positive smears were found in 79.5%patients while 20.45% cases were AFB negative. Among AFB negative smears, 38 cases were further analyzed by PCR, among which 32 (84.2%) cases showed PCR positive results for TM. An increased frequency of TM among all inflammatory breast lesions from 18% in 2008 to 47.19% in 2018 was observed. Conclusion:Tuberculous Mastitis is an uncommon form of extra-pulmonary tuberculosis. It has nonspecific clinical, radiological and varied histological findings that often mimic breast abscess or carcinoma. FNAC is essential to guide the patient to further tests including histochemistry and PCR that can be used as more sensitive and time effective detection modalities.

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Section: Discussionmentioning

confidence: 71%

Tuberculous Mastitis in Females of South Punjab: A Clinicopathological Analysis of Ten Years from Pakistan

Samad¹,

Bukhar²,

Sartaj³

et al. 2020

BIOMEDICA

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“…The risk factors reported in the literature are multiparty, breastfeeding, breast trauma and chronic mastitis [3]. Tuberculous mastitis affects mainly women of reproductive age [6], usually (83% to 95% of cases), between 20 and 40 years [7]. For Mehta G et al [8], 49.2% of women were under 30 years old.…”

Section: Discussionmentioning

confidence: 99%

Primary Breast Tuberculosis Mimicking Carcinomatous Mastitis: A Case Report

Raivoherivony¹,

Nomenjanahary²,

Rakotondrainibe³

et al. 2021

OJPathology

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The breast is a rare localization of extra-pulmonary tuberculosis, even in highly endemic countries. It is most often primitive. The clinical and radiological features are sometimes misleading. It poses diagnostic problems especially with cancer. We report a case of breast tuberculosis having clinical and radiological presentations as a breast carcinoma. Through this observation and a review of the literature, we provide an update on the epidemiological characteristics and the means of diagnosis of this lesion. It was a 52-year-old woman with inflammatory lump of the left breast, adherent to the skin. Ultrasonography and mammography revealed a homogeneous, poorly demarcated nodule of approximately 4 cm of diameter, classified ACR4. Surgical excision was performed. The histological diagnosis was breast tuberculosis. The diagnosis of tuberculous mastitis is made on bacteriological and pathological examinations. Histological examination helps for diagnostic confirmation while excluding a malignant lesion of the breast.

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“…The clinical presentation and radiological findings in primary mammary TB are often misleading 2 . There is a lack of awareness about its presentation among healthcare professionals, leading to its oversight in the majority of patients 16 , 17 .…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Challenge: A case report of primary breast tuberculosis mimicking recurrent pyogenic breast abscess

Thapaliya,

Kumari,

Oli

et al. 2024

Annals of Medicine &Amp; Surgery

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Introduction: Breast tuberculosis is a rare form of extra pulmonary tuberculosis with its primary form considered even rarer. Case presentation: A 28-year-old female initially diagnosed with a breast abscess presented with chronic right breast pain and nipple discharge. Despite initial treatment, symptoms recurred, and further investigations revealed a space-occupying lesion. Fine needle aspiration confirmed recurrent breast abscess, but subsequent DNA detection of tubercular bacilli in the pus sample led to a diagnosis of primary breast tuberculosis, necessitating anti-tubercular therapy. Clinical discussion: Breast tuberculosis, being rare and often misdiagnosed as an abscess, poses diagnostic challenges. However, Persistent symptoms despite treatment should prompt consideration of breast tuberculosis in TB endemic regions. Conclusion: Primary Breast Tuberculosis might not have any systemic symptoms to drag the clinician towards a possible diagnosis so culturing the aspirate for acid-fast bacilli or looking for MTB DNA in the available clinical sample should always be kept in mind for better outcomes.

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Breast tuberculosis, a rare entity

Cited by 9 publications

References 6 publications

Tuberculous Mastitis in Females of South Punjab: A Clinicopathological Analysis of Ten Years from Pakistan

Tuberculous Mastitis in Females of South Punjab: A Clinicopathological Analysis of Ten Years from Pakistan

Primary Breast Tuberculosis Mimicking Carcinomatous Mastitis: A Case Report

Diagnostic Challenge: A case report of primary breast tuberculosis mimicking recurrent pyogenic breast abscess

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