Breastfeeding modulates neonatal innate immune responses: a prospective birth cohort study

Belderbos, Mirjam E.; Houben, Michiel L.; Bleek, Grada M. van; Schuijff, Leontine; Uden, Nathalie O. van; Bloemen-Carlier, Eltje M.; Kimpen, Jan L. L.; Eijkemans, M. J. C.; Rovers, Maroeska M.; Bont, Louis

doi:10.1111/j.1399-3038.2011.01230.x

Cited by 70 publications

(63 citation statements)

References 33 publications

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“…Innate immune responses differ between breast-fed and formula-fed infants during the first month of life (39). Later differences in systemic inflammatory parameters have only been shown in selected groups; breast feeding was associated with higher CRP in adolescents in a follow-up study on preterm infants (9) but not in another study on term infants (40).…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular risk markers until 12 mo of age in infants fed a formula supplemented with bovine milk fat globule membranes

et al. 2014

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Background: Some of the health advantages of breast-fed as compared to formula-fed infants have been suggested to be due to metabolic programming effects resulting from early nutrition. Methods: In a prospective double-blinded randomized trial, 160 infants <2 mo of age were randomized to experimental formula (EF) with added milk fat globule membrane (MFGM) or standard formula (SF) until 6 mo of age. A breast-fed reference (BFR) group consisted of 80 infants. Measurements were made at inclusion and at 4, 6, and 12 mo of age. results: During the intervention, the EF group had higher total serum cholesterol concentration than the SF group, reaching the level of the BFR group. The EF group had a low-density lipoprotein to high-density lipoprotein ratio not significantly different from the SF group but lower than the BFR group. conclusion: Supplementation of infant formula with MFGM modified the fat composition of the formula and narrowed the gap between breast-fed and formula-fed infants with regard to serum lipid status at 12 mo.

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Section: Discussionmentioning

confidence: 99%

Cardiovascular risk markers until 12 mo of age in infants fed a formula supplemented with bovine milk fat globule membranes

et al. 2014

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“…14,15 The development of asthma and allergic disease might be mediated by the innate immune system and its orchestration of complex immune cascades. 1 The first stages of life seem critical for the maturation of the innate immune system, 16 but little is known about the development of gene expression over time and the relevant environmental exposures influencing it.…”

mentioning

confidence: 99%

Prenatal and early-life exposures alter expression of innate immunity genes: The PASTURE cohort study

Loss

Bitter

Wohlgensinger

et al. 2012

Journal of Allergy and Clinical Immunology

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“…Our immune systems have evolved to respond to infections shortly after birth, usually through the mother's antibodies during breast-feeding. 25,26 The immune systems of children exposed at later ages, without having confronted microbes at an earlier age, may not respond as well. These children may have increased risk of developing leukemia.…”

Section: Resultsmentioning

confidence: 99%

Medicine in Philately Hematology and Oncology with Stamps

Ataman¹

2013

UHOD

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The importance given to blood and the understanding of cancer are the two oldest features of medical history. These two concepts are combined in our current description as hematologic oncology. Today the three main types of blood cancer are known as lymphoma, leukemia and multiple myeloma. Each varies slightly in terms of treatment, prognosis and symptoms. Beginning from the discovery of blood circulation and blood grouping, with many new techniques in diagnosis and treatment modalities; the approach to hematology and oncology evolved a lot. This paper provides an overview to the main historical aspects of hematology and leukemia through philately.Keywords: Hematology, Leukemia, Pathology, History, Philately ÖZET Filatelide T›p, Pullarla Hematoloji ve OnkolojiKana verilen önem ve kanserin tan›nmas› t›p tarihinin en eski iki olgusudur. Bu iki kavram günümüzde hematolojik onkoloji tan›m›yla biraraya getirilmifltir. Bugün bilinen üç kan kanseri türü lenfoma, lösemi ve multiple myeloma olarak s›n›fland›r›lmaktad›r. Her biri tedavi prognoz ve semptomlar aç›s›ndan farkl›l›klar göstermektedir. Hematoloji ve onkoloijiye yaklafl›m›m›z gerek kan dolafl›-m› ve kan gruplar›n›n keflfi gerekse tan› ve tedaviye yönelik birçok yeni tekni¤in geliflmesiyle birlikte köklü bir evrime u¤ram›flt›r. Bu ça-l›flma hematoloji ve löseminin temel tarihsel sürecine filateli arac›l›¤› ile genel bir bak›fl sunmay› hedeflemektedir.

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Breastfeeding modulates neonatal innate immune responses: a prospective birth cohort study

Abstract: Neonatal innate immune responses are differentially modulated by environmental exposure in the first month of life. The protective effect of breastfeeding against subsequent infections and atopy might be explained by its innate immune modulatory effects in the first month of life.

Cited by 70 publications

References 33 publications

Cardiovascular risk markers until 12 mo of age in infants fed a formula supplemented with bovine milk fat globule membranes

Cardiovascular risk markers until 12 mo of age in infants fed a formula supplemented with bovine milk fat globule membranes

Prenatal and early-life exposures alter expression of innate immunity genes: The PASTURE cohort study

Medicine in Philately Hematology and Oncology with Stamps

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