Breath test is very reliable for diagnosis of Helicobacter pylori infection in real clinical practice

Gomollón, Fernando; Ducóns, Julio; Santolaria, Santos; Omiste, I. Lera; Guirao, R.; Ferrero, Miguel Pérez; Montoro, Miguel

doi:10.1016/s1590-8658(03)00373-6

Cited by 28 publications

(16 citation statements)

References 22 publications

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“…Gomollon et al. reported that the urea breath test is a reliable method for diagnosis of H. pylori infection in routine clinical practice and that there is no indication to obtain biopsies for histologic diagnosis of H. pylori [48]. We believe that the urea breath test reflects the exact prevalence of H. pylori infection in our study population.…”

Section: Discussionmentioning

confidence: 77%

“…Another limitation of this study was that the H. pylori infection was determined by urea breath test and stomach biopsy was not done; thus, H. pylori infection could not be confirmed histolopathologically. Gomollon et al reported that the urea breath test is a reliable method for diagnosis of H. pylori infection in routine clinical practice and that there is no indication to obtain biopsies for histologic diagnosis of H. pylori [48]. We believe that the urea breath test reflects the exact prevalence of H. pylori infection in our study population.…”

Section: Study Limitationsmentioning

confidence: 69%

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Elevated Homocysteine Levels in Patients with Slow Coronary Flow: Relationship with Helicobacter pylori Infection

et al. 2007

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Our data showed that plasma folate levels were decreased and plasma Hcy levels were increased in patients with SCF compared to controls. Also, the prevalence of H. pylori infection was increased in patients with SCF. These findings suggest that elevated levels of plasma Hcy, possibly caused by H. pylori infection, and/or a possible disturbance in its metabolism may play a role in the pathogenesis of SCF.

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Section: Discussionmentioning

confidence: 77%

Section: Study Limitationsmentioning

confidence: 69%

Elevated Homocysteine Levels in Patients with Slow Coronary Flow: Relationship with Helicobacter pylori Infection

et al. 2007

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“…However, the UBT has proven to be highly accurate and reproducible. 1,2,25,26 These results suggest that use of an acidified 14 C-urea capsule cannot prevent false negative UBT results in patients taking pantoprazole and ranitidine and the duration of medication does not affect the test results. 17 1998…”

Section: Discussionmentioning

confidence: 91%

“…We have not formally tested this question in our department. However, the UBT has proven to be highly accurate and reproducible 1,2,25,26 …”

Section: Discussionmentioning

confidence: 99%

“…C-Urea Breath Test (UBT) is a reliable, reproducible and noninvasive technique in the diagnosis of Helicobacter pylori (HP) infection. 1,2 A number of factors such as recent use of antibiotics, bismuth compounds or anti-secretory drugs have been found to affect the accuracy of UBT. 3,4 Variable false negative test results (25-61%) have been reported in patients using anti-secretory drugs before UBT.…”

Section: Introductionmentioning

confidence: 99%

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Performance of acidified ¹⁴C‐urea capsule breath test during pantoprazole and ranitidine treatment

Öztürk¹,

Yeşilova²,

Ilgan³

et al. 2009

J of Gastro and Hepatol

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Non-invasive diagnostic tests forHelicobacter pyloriinfection

Best

Takwoingi

Siddique

et al. 2018

Cochrane Database of Systematic Reviews

158

130

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In people without a history of gastrectomy and those who have not recently had antibiotics or proton ,pump inhibitors, urea breath tests had high diagnostic accuracy while serology and stool antigen tests were less accurate for diagnosis of Helicobacter pylori infection.This is based on an indirect test comparison (with potential for bias due to confounding), as evidence from direct comparisons was limited or unavailable. The thresholds used for these tests were highly variable and we were unable to identify specific thresholds that might be useful in clinical practice.We need further comparative studies of high methodological quality to obtain more reliable evidence of relative accuracy between the tests. Such studies should be conducted prospectively in a representative spectrum of participants and clearly reported to ensure low risk of bias. Most importantly, studies should prespecify and clearly report thresholds used, and should avoid inappropriate exclusions.

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Breath test is very reliable for diagnosis of Helicobacter pylori infection in real clinical practice

Cited by 28 publications

References 22 publications

Elevated Homocysteine Levels in Patients with Slow Coronary Flow: Relationship with Helicobacter pylori Infection

Elevated Homocysteine Levels in Patients with Slow Coronary Flow: Relationship with Helicobacter pylori Infection

Performance of acidified ¹⁴C‐urea capsule breath test during pantoprazole and ranitidine treatment

Non-invasive diagnostic tests forHelicobacter pyloriinfection

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Breath test is very reliable for diagnosis of Helicobacter pylori infection in real clinical practice

Cited by 28 publications

References 22 publications

Elevated Homocysteine Levels in Patients with Slow Coronary Flow: Relationship with Helicobacter pylori Infection

Elevated Homocysteine Levels in Patients with Slow Coronary Flow: Relationship with Helicobacter pylori Infection

Performance of acidified 14C‐urea capsule breath test during pantoprazole and ranitidine treatment

Non-invasive diagnostic tests forHelicobacter pyloriinfection

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Product

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Performance of acidified ¹⁴C‐urea capsule breath test during pantoprazole and ranitidine treatment