Breathable, Antibacterial, and Biocompatible Collagen Fiber Network Decorated with Zwitterionic Silver Nanoparticles for Plantar Pressure Monitoring

Abstract

Foot plantar pressure monitoring and gait analysis are of great significant in footwear design, sport biomechanics, injury prevention, and early warning of disease. Flexible and wearable smart insoles pave a feasible way for these application scenarios. However, the majority of the currently developed smart insoles are composed of synthetic polymers (e.g., plastics, rubbers, etc.), leading to inevitable problems associated with air permeability, hygiene condition, biocompatibility, and wearing comfort. Here, a new paradigm of a natural collagen fiber network (CFN) with soft and breathable features, which can be obtained by facilely treating animal hides via conventional leather pretreatment process, is selected as substrate material for constructing smart insoles due to its high permeability and porosity. Further, biocompatible zwitterionic silver nanoparticles (AgNPs) with both carboxybetaine and catechol groups on the interface were designed for firmly and uniformly immobilization onto the hierarchical micro-/nanoscale fibers of CFN through mussel-inspired catechol/amino chemistry, giving rise to both good antibacterial property and pressure sensing capability of the resultant material. The finally developed smart insole by using the AgNPs decorated CFN exhibits good capability for plantar pressure mapping and gait feature analysis. Especially, the smart insole will be very suitable for pressure monitoring and gait analysis of a diabetic foot with sensitive skin that requires a high biocompatible and antibacterial environment.

A zwitterionic silver nanoparticle-incorporating injectable hydrogel with a durable and efficient antibacterial effect for accelerated wound healing

“…1h and i could be correlated with their antibacterial performances against antibiotic-resistant strains. The broad-spectrum antibacterial activity was consistent with our previous research 28,41,[45][46][47] on polycarboxybetaine-modified AgNPs and copper-phenolic networks, which suggested that the strategy of polyzwitterionic functionalization could provide the potential to address the challenge of aggregation-related resistance.…”

Versatile nano–micro collagen fiber-based wearable electronics for health monitoring and thermal management

“…[76][77][78] Since the rate of resistance changes to PPy/ SCB@PP-CFs is stable when retaining the same touch action, Morse code can be generated based on the duration of nger touching. The electrical signal induced by short-term touching [79][80][81][82][83][84][85][86][87][88][89][90][91][92] This journal is © The Royal Society of Chemistry 2023 exhibited a spike, representing a "dot", and the electrical signal induced by long-term touching demonstrated a straight line, representing a "dash" (Fig. 5A).…”

“…7L), which demonstrates the ability of the modied shoe to provide real-time status monitoring and visual data feedback on human movement. To demonstrate the advantages of PPy/SCB@PP-CFs in future smart, exible strain sensors, PPy/SCB@PP-CFs are comprehensively compared to some of the previously reported multifunctional exible strain sensors, which are based on CFs, [79][80][81][82] other natural biomass bers, [83][84][85][86] synthetic bers, [87][88][89][90] and nanocomposite hydrogels 91,92 in terms of the tensile/compression strength, air permeability, biocompatibility, super-amphiphobic properties, ame-retardant properties, EMI shielding effectiveness, energy conversion performance, and strain-sensing performance (Fig. 7M).…”

Collagen-Supported Amino-Functionalized Ag@SiO2 Core–Shell Nanoparticles for Visible-Light-Driven Water Remediation

“…for the binding of CS NPs via covalent or non-covalent bonding. 46,47 Further, collagen-based materials offer high porosity due to their hierarchical network structure and easy processability from industrial bio-wastes, 48 which make them an ideal material for cost-effective and environmentally benign photocatalyst supports.…”

“…Here, natural biopolymers such as collagen could perform as an ideal substrate in terms of easy biodegradability, recoverability, recyclability, and good compatibility with a nanocatalyst by providing functional groups (−COOH, −NH 2 , etc.) for the binding of CS NPs via covalent or non-covalent bonding. , Further, collagen-based materials offer high porosity due to their hierarchical network structure and easy processability from industrial bio-wastes, which make them an ideal material for cost-effective and environmentally benign photocatalyst supports.…”