Bredspektrede antibiotika i norske sykehus

Holen, Øyunn; Alberg, Torunn; Blix, Hege Salvesen; Smith, Ingrid; Neteland, Marion Iren; Eriksen, Hanne-Merete

doi:10.4045/tidsskr.16.0622

Cited by 11 publications

(2 citation statements)

References 10 publications

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“…23 Further, 40.9% of children hospitalized on the day of PPS were found to be prescribed AMA in a UKbased study. 24 The present survey has revealed a high prevalence of infectious disease burden and antimicrobial usage in acute wards of our hospital. But the burden of infections is still very high even in developed nations and needs coordinated efforts to reduce the existing prevalence.…”

Section: Discussionmentioning

confidence: 73%

A point prevalence survey of antimicrobial agents and antibiotic susceptibility patterns of admitted patients in acute wards of a teaching hospital in Western India

Jaiswal¹,

Shyam²

2019

IJPP

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Introduction: Antimicrobial stewardship programme (AMSP) is an important strategy to contain antimicrobial resistance (AMR) in the community. Materials and Methods: A point prevalence survey was carried out in October 2018 in accordance with ECDC 2013 document. The survey was carried out on a single day in intensive care units, acute medical, acute surgical and family wards of a tertiary care hospital in western India. Results: Less than 44% of admitted patients in acute wards were found to be prescribed with antimicrobial agents (AMA). The culture report of clinical specimen sent was positive for pathogen growth in 21% samples. Cephalosporins, penicillins and quinolones were the most commonly prescribed AMA on inpatients of the hospital. Of these, 70% were administered parenterally and 46% were given for more than one week. 70% of the empirical therapy was found to be effective. Pathogens resistant to many WHO WATCH group AMA and aztreonam, a RESERVE AMA have been isolated in the survey. Two of the isolated pathogens showed sensitivity to less than 3 antibiotics. Conclusion:The present survey has revealed a high prevalence of infectious disease burden and antimicrobial usage in acute wards of our hospital.

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Section: Discussionmentioning

confidence: 73%

A point prevalence survey of antimicrobial agents and antibiotic susceptibility patterns of admitted patients in acute wards of a teaching hospital in Western India

Jaiswal¹,

Shyam²

2019

IJPP

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“…Antibacterial medications were abstracted by matching drug names with the Anatomical Therapeutic Chemical (ATC) classification system (World Health Organization Collaborating Centre for Drug Statistics Methodology) [ 23 ] to identify drug categories. Second-generation cephalosporins (J01DC), third-generation cephalosporins (J01DD), fourth-generation cephalosporins (J01DE), fluoroquinolones (J01MA), macrolides (J01FA, except erythromycin J01FA01), penicillins with extended-spectrum (J01CA), combinations of penicillins including beta-lactamase inhibitors (J01CR), carbapenems (J01DH), and streptomycins (J01GA) were classified as broad-spectrum antibiotics [ 19 , 24 , 25 ]. The other antibiotics were classified as narrow-spectrum antibiotics.…”

Section: Methodsmentioning

confidence: 99%

Identifying Risk Factors for Aspiration in Patients Hospitalized with Community-Acquired Pneumonia

Zhao

Zhang

Wang

et al. 2023

International Journal of Clinical Practice

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Background. Aspiration pneumonia (AP) is difficult to diagnose and has poor outcomes. This case-control study aimed to explore the risk factors and delineate the antibiotic usage for AP. Methods. Inpatients diagnosed with community-acquired pneumonia (CAP) from 2013 to 2017, enrolled in the urban employee basic medical insurance program in Beijing, were included and classified into the AP (N = 2,885) and non-AP (N = 53,825) groups. Risk factors were identified by logistic regression. Results. Older age (compared to 18–64 years, OR for 65–79 years: 4.3, 95% CI: 3.8–4.9; OR for >80 years: 6.3, 95% CI: 5.6–7.2), male (OR: 1.4, 95% CI: 1.3–1.5), cerebrovascular disease (OR: 3.1, 95% CI: 2.8–3.5), dementia (OR: 2.0, 95% CI: 1.8–2.1), vomiting (OR: 1.4, 95% CI: 1.2–1.7), Parkinson’s disease (OR: 2.1, 95% CI: 1.8–2.4), and epilepsy (OR: 3.2, 95% CI: 2.8–3.7) were associated with an increased risk of AP. 92.8% of the AP patients received antibiotic therapy. Among them, patients treated with broad-spectrum antibiotics, antibiotics for injection, and combined antibiotics accounted for 93.3%, 97.9%, and 81.7%, respectively. Conclusions. Older age, male, and several comorbidities were independent risk factors for AP, and combined antibiotics treatments are common, which merits attention in accurate detection of AP in a high-risk population.

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Point-of-Care Influenza Testing Impacts Clinical Decision, Patient Flow, and Length of Stay in Hospitalized Adults

Fjelltveit

Østensjø

Blomberg

et al. 2020

The Journal of Infectious Diseases

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Background Influenza is difficult to distinguish clinically from other acute respiratory infections. Rapid laboratory diagnosis can help initiate early effective antiviral treatment and isolation. Aim Implementing a novel point-of-care test (POCT) for influenza in the emergency department (ED) could improve treatment and isolation strategies and reduce the length-of-stay (LOS). Methods In a prospective, controlled observational cohort study, we enrolled patients admitted due to acute respiratory illness to two public hospitals in Bergen, Norway, one using a rapid POCT for influenza (n=400), the other (n=167) using conventional rapid lab-based assay. Results The prevalence of influenza was similar in the two hospitals (154/400, 38% versus 38%, 63/167, p=0.863), and most patients in both hospitals received antiviral (83% versus 81%,p=0.703) and antibiotic treatment (76% versus 73%, p= 0.469). Isolation was more often initiated in the ED in the hospital using POCT (91% versus 80%, p=0.025). Diagnosis by POCT was associated with shorter hospital stay, while old age, diabetes, cancer, use of antibiotics, particularly broad-spectrum antibiotics, were associated with prolonged stay. Conclusions POCT implementation in the ED resulted in improved targeted isolation and shorter LOS. Regardless of POCT-use, most influenza patients received antivirals (>80%) and antibiotics (>70%).

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Bredspektrede antibiotika i norske sykehus

Cited by 11 publications

References 10 publications

A point prevalence survey of antimicrobial agents and antibiotic susceptibility patterns of admitted patients in acute wards of a teaching hospital in Western India

A point prevalence survey of antimicrobial agents and antibiotic susceptibility patterns of admitted patients in acute wards of a teaching hospital in Western India

Identifying Risk Factors for Aspiration in Patients Hospitalized with Community-Acquired Pneumonia

Point-of-Care Influenza Testing Impacts Clinical Decision, Patient Flow, and Length of Stay in Hospitalized Adults

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