The COVID-19 pandemic has drawn worldwide attention to the difficulties inherent in managing disasters. Scholars across disciplines have been forced to consider the impact disasters have on interstate relations, state resilience, patterns of violence and hostility, and the vulnerabilities that condition conflict. This special issue offers new insights to help disentangle the relationship between disasters, conflict, and cooperation, by adhering to a three-pronged theoretical framework. First, all pieces in this issue are underpinned by a unified understanding of disasters as endogenous social phenomena. Second, we acknowledge that disasters occur as processes rather than discrete events. Finally, we explore the possibility that disasters and conflict are co-determined by a common set of factors. The articles herein were chosen not only because they advance academic thought about the disaster–conflict nexus, but also because of their potential to advance the practical impact of this line of research on the global conflict and disaster landscape. We highlight the relevance of this special issue for further work investigating the effects of conflict on disasters and the relationship between the hazards cycle process and patterns of violence and hostility, as well as the implications of adopting this suggested framework for policymaking and data collection.