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Stricker, Daniel

doi:10.1016/j.cmpb.2008.06.010

Cited by 77 publications

(54 citation statements)

References 29 publications

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“…Ordinal values from 1 (very important) to 5 (very unimportant) were assigned to ratings and unsure responses were treated as missing data for the purpose of analysis. A Friedman two-way analysis of variance (Stricker, 2008) was conducted to determine whether decision-making factors were ranked differently by participants. There were significant differences in the rankings, χ 2 (5, N = 271) = 199.38, p < .0001, so Conover post hoc comparisons were completed.…”

Section: Resultsmentioning

confidence: 99%

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Factors in Instructional Decision-Making, Ratings of Evidence and Intended Instructional Practices of Australian Final Year Teacher Education Students

Carter

Stephenson

Hopper

2015

AJTE

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Section: Resultsmentioning

confidence: 99%

“…A Friedman two-way analysis of variance (Stricker, 2008) was conducted to determine whether evidence for practices was ranked differently by participants. There were significant differences in the rankings, χ 2 (13, N = 153) = 236.43, p < .0001, so Conover post hoc comparisons were completed.…”

Section: Resultsmentioning

confidence: 99%

Factors in Instructional Decision-Making, Ratings of Evidence and Intended Instructional Practices of Australian Final Year Teacher Education Students

Carter

Stephenson

Hopper

2015

AJTE

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“…Games-Howell using BrightStat [18]. Except for the Games-Howell test, statistical calculations were performed in JMP 6.0 (SAS Institute, Cary, NC, USA) or MATLAB R2009a (The MathWorks, Inc. Massachusetts, USA).…”

Section: Statisticsmentioning

confidence: 99%

Quantifying differences in hepatic uptake of the liver specific contrast agents Gd-EOB-DTPA and Gd-BOPTA: a pilot study

et al. 2011

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Objectives: To develop and evaluate a procedure for quantifying the hepatocyte-specific uptake of Gd-BOPTA and Gd-EOB-DTPA using Dynamic Contrast-Enhanced (DCE) MRI. Methods:Ten healthy volunteers were prospectively recruited and 21 patients with suspected hepatobiliary disease were retrospectively evaluated. All subjects were examined with DCE-MRI using 0.025 mmol/kg of Gd-EOB-DTPA. The healthy volunteers underwent an additional examination using 0.05 mmol/kg of Gd-BOPTA. The signal intensities (SI) of liver and spleen parenchyma were obtained from unenhanced and enhanced acquisitions. Using pharmacokinetic models of the liver and spleen and an SI rescaling procedure, a hepatic uptake rate, K Hep , estimate was derived. K Hep values for Gd-EOB-DTPA were then studied in relation to those for Gd-BOPTA and to a clinical classification of the patient's hepatobiliary dysfunction. ; P <0.01). Results: K Conclusions:A new procedure for quantifying the hepatocyte-specific uptake of T 1 -enhancing contrast agent was demonstrated and used to show that impaired hepatobiliary function severely influences the hepatic uptake of Gd-EOB-DTPA.

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“…The normal distribution of the collected data was tested using the ShapiroWilk normality test in the "R" software suite (R development team 2011). To determine statistical significance among data sets, depending on normality of the data and number of data sets compared, one-way ANOVA, the Kruskal-Wallis test, or an independent t-test in Brightstat (Stricker 2008) was used. The correlations between CtCAD expression and specific activity of total plant protein towards coniferaldehyde and sinapaldehyde were determined by linear regression and Pearson correlation tests in Brightstat (Stricker 2008).…”

Section: Discussionmentioning

confidence: 99%

Characterization of three cinnamyl alcohol dehydrogenases from Carthamus tinctorius

Ragamustari

Shiraiwa

Hattori

et al. 2013

Plant Biotechnology

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We report the isolation and characterization of three cDNAs encoding cinnamyl alcohol dehydrogenase (CAD) from Carthamus tinctorius (safflower). All three recombinant CADs were able to reduce coniferaldehyde and sinapaldehyde into coniferyl alcohol and sinapyl alcohol, respectively, and were designated as CtCAD1, CtCAD2, and CtCAD3. Phylogenetic analysis of CAD amino acid sequences and homology modeling revealed that CtCAD1 and CtCAD3 were closely related to the sinapaldehyde-specific aspen (Populus tremuloides) sinapyl alcohol dehydrogenase (PtreSAD). CtCAD2 was in a clade containing class I plant CADs. Gas chromatography-mass spectrometry-based kinetic analysis using two different substrates, coniferaldehyde and sinapaldehyde, indicated that the CtCADs showed no strong preference for either substrate. CtCAD2 has the highest catalytic efficiency (k cat /K m ) (81.49 mM −1 min −1 and 95.3 mM −1 min −1 for coniferaldehyde and sinapaldehyde, respectively) compared with the other CtCADs. Inhibition kinetics showed that coniferaldehyde was a stronger inhibitor than sinapaldehyde for all CtCADs. Quantitative real-time PCR revealed that CtCAD2 was expressed at higher levels than CtCAD1 and CtCAD3 in all samples, except developing seeds at 3 days after flowering, where CtCAD1 had a higher expression level. In plant protein assays with coniferaldehyde and sinapaldehyde, plant protein extracted from seeds at 7 days after flowering, showed the highest specific activity. The product yields in plant protein assays were strongly correlated with gene expressions of CtCAD2 and CtCAD3 in the respective organs.

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Cited by 77 publications

References 29 publications

Factors in Instructional Decision-Making, Ratings of Evidence and Intended Instructional Practices of Australian Final Year Teacher Education Students

Factors in Instructional Decision-Making, Ratings of Evidence and Intended Instructional Practices of Australian Final Year Teacher Education Students

Quantifying differences in hepatic uptake of the liver specific contrast agents Gd-EOB-DTPA and Gd-BOPTA: a pilot study

Characterization of three cinnamyl alcohol dehydrogenases from Carthamus tinctorius

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