Graphene has emerged as an attractive material for a myriad of optoelectronic applications due to its variety of remarkable optical, electronic, thermal and mechanical properties. So far, the main focus has been on graphene based photonics and optoelectronics devices. Due to the linear band structure allowing interband optical transitions at all photon energies, graphene has remarkably large third-order optical susceptibility χ (3) , which is only weakly dependent on the wavelength in the near-infrared frequency range. Graphene possesses the properties of the enhancement four-wave mixing (FWM) of conversion efficiency. So, we believe that the potential applications of graphene also lies in nonlinear optical signal processing, where the combination of its unique large χ (3) nonlinearities and dispersionless over the wavelength can be fully exploited. In this chapter, we give a brief overview of our recent progress in graphene-assisted nonlinear optical device which is graphene-coated optical fiber and graphene-silicon microring resonator and their applications, including degenerate FWM based tunable wavelength conversion of quadrature phase-shift keying (QPSK) signal, two-input optical computing, three-input high-base optical computing, graphene-silicon microring resonator enhanced nonlinear optical device for on-chip optical signal processing, and nonlinearity enhanced graphenesilicon microring for selective conversion of flexible grid multi-channel multi-level signal.