Bronchopulmonary Dysplasia

Kair, Laura R.; Leonard, Douglas; Anderson, JoDee M.; MEd,

doi:10.1542/pir.33.6.255

Cited by 19 publications

(16 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The nding that the risk of BPD is inversely related to birth weight and gestational age at birth is consistent with existing literature [19,20]. Infants born prematurely have underdeveloped lungs and stressors that contribute to their prematurity.…”

Section: Discussionsupporting

confidence: 90%

Establishment and efficiency analysis of the risk prediction model predicting the likelihood of bronchopulmonary dysplasia in preterm infants: A retrospective observational study

SUO¹,

Qi²,

Yang³

et al. 2022

Preprint

View full text Add to dashboard Cite

Background Clinically useful and adequately validated predictive models of bronchopulmonary dysplasia (BPD) available at or soon after birth, especially for the Chinese population are few. This study aims to develop and validate a predictive model for the identification of BPD at early stage and the generation of a nomogram for clinical use.Methods This retrospective study developed a well-validated predictive model of BPD among preterm infants with gestational age (GA) of less than 32 weeks by logistic regression and generated a nomogram.Results This model comprised six variables, i.e., GA, birthweight, neonatal asphyxia, invasive ventilation, neonatal respiratory distress syndrome (NRDS), and patent ductus arteriosus (PDA). The regression equation was Logit P = (15.209 – 0.076 × GA – 1.001 × birthweight + 0.557 × neonatal asphyxia + 1.083 × invasive ventilation + 0.622 × NRDS + 0.656 × PDA). The area under the receiver operating characteristic (ROC) curve of this model was 0.856 (95% CI: 0.812–0.901), with sensitivity of 81.6% and specificity of 76.8%. The verification of this predictive model showed a sensitivity of 93.5% and specificity of 76.5%, demonstrating that the effects of this model were satisfactory.Conclusions This risk prediction model had a good predictive effect for the risk of BPD in premature infants with GA less than 32 weeks and could furnish evidence for preventive treatment and intervention.

show abstract

Section: Discussionsupporting

confidence: 90%

Establishment and efficiency analysis of the risk prediction model predicting the likelihood of bronchopulmonary dysplasia in preterm infants: A retrospective observational study

SUO¹,

Qi²,

Yang³

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…BPD was defined as the need for a continuous supplemental oxygen concentration > 21% by nasal cannula, nasal catheter, face mask or respiratory support for at least 28 continuous days or by corrected age of 36 weeks, or more than 56 days of postnatal age for infants born after more than 32 weeks gestation [ 16 ].…”

Section: Methodsmentioning

confidence: 99%

Effectiveness and safety of early versus late caffeine therapy in managing apnoea of prematurity among preterm infants: a retrospective cohort study

et al. 2022

View full text Add to dashboard Cite

Background Early administration of intravenous (IV) caffeine (initiation within 2 days of life) is an effective treatment strategy for the management of apnoea of prematurity among infants. However, the safety and effectiveness of early administration of oral caffeine treatment is not be fully established. Aim We aimed to compare the effectiveness and safety of early versus late caffeine therapy on preterm infants’ clinical outcomes. Method A retrospective matched cohort study was conducted using data of patients admitted to neonatal intensive care units of two tertiary care hospitals between January 2016 and December 2018. The clinical outcomes and mortality risk between early caffeine (initiation within 2 days of life) and late caffeine (initiation ≥ 3 days of life) were compared. Results Ninety-five pairs matched based on gestational age were included in the study. Compared to late initiation, preterm infants with early caffeine therapy had: a shorter duration of non-invasive mechanical ventilation (median 5 days vs. 12 days; p < 0.001); shorter length of hospital stay (median 26 days vs. 44 days; p < 0.001); shorter duration to achieve full enteral feeding (median 5 days vs. 11 days; p < 0.001); and lower frequency of bronchopulmonary dysplasia (BPD) (4.5% vs. 12.9%; p = 0.045). They also had a reduced risk of osteopenia of prematurity (OP) (OR 0.209; 95% CI 0.085–0.509; p = 0.001). Conclusion Early oral caffeine therapy can potentially improve respiratory outcomes among infants with apnoea of prematurity. However, an increase in mortality associated with early caffeine therapy requires further investigation.

show abstract

“…Термин БЛД является предметом обсуждений с тех пор, как были предложены первоначальные критерии диагностики [3][4][5]. Первоначальные критерии включали младенцев с потребностью в кислороде в течение 28 дней с сопутствующими рентгенографическими изменениями [5,6]. Shennan и др.…”

Section: определениеunclassified

Current Understanding of Bronchopulmonary Dysplasia (Literature Review)

Улезко¹,

Девялтовская²,

Левандовский³

2022

Репродуктивное Здоровье. Восточная Европа

View full text Add to dashboard Cite

Определение бронхолегочной дисплазии являлось предметом обсуждений с тех пор, как были предложены первоначальные критерии диагностики. С течением времени и развитием новых технологий критерии диагностики претерпели ряд существенных изменений. Использование сурфактант-заместительной терапии, совершенствование техник выхаживания недоношенных новорожденных детей, модернизация отделений реанимации, эволюция технологий мониторинга состояния кислотно-щелочной системы и определения уровней газов крови, широкое применение метода компьютерной томографии, глубокие познания в патофизиологии и патогенезе развития и течения заболевания способствовали постоянной модернизации понимания проблематики бронхолегочной дисплазии как на уровнях диагностики и терапии, так и на классификационных и семантических уровнях. В статье представлены последние данные анализа мировых литературных источников о бронхолегочной дисплазии как самостоятельной нозологической единице. The definition of bronchopulmonary dysplasia has been the subject of debate since the original diagnostic criteria were proposed. With the passage of time and the development of new technologies, the diagnostic criteria have undergone a number of significant changes. The era of surfactant replacement therapy, improvement of nursing techniques for premature infants, modernization of intensive care units, evolution of acid-base system monitoring and blood gas levels, widespread introduction and use of computed tomography, profound knowledge of pathophysiology and pathogenesis of the development and course of the disease – all this has contributed to the continuous modernization of understanding of bronchopulmonary dysplasia, both at the diagnostic and therapy levels and at classification The article presents the latest data of the world literature analysis of bronchopulmonary dysplasia as an independent nosological unit.

show abstract

Bronchopulmonary Dysplasia

Cited by 19 publications

References 31 publications

Establishment and efficiency analysis of the risk prediction model predicting the likelihood of bronchopulmonary dysplasia in preterm infants: A retrospective observational study

Establishment and efficiency analysis of the risk prediction model predicting the likelihood of bronchopulmonary dysplasia in preterm infants: A retrospective observational study

Effectiveness and safety of early versus late caffeine therapy in managing apnoea of prematurity among preterm infants: a retrospective cohort study

Current Understanding of Bronchopulmonary Dysplasia (Literature Review)

Contact Info

Product

Resources

About