Bronchopulmonary dysplasia predictor scale validation in preterm newborns in two neonatal units at 2600 m above sea level

Vásquez, Pablo; Diaz, Hector Alfonso Romero; Gomez, Maria Juanita Gomez; Leal, Lida; Navarro, Lorena Margarita Yejas

doi:10.1016/j.infbeh.2018.04.001

Cited by 6 publications

(5 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Oxygen requirement is defined as when the patient presents saturation values for hemoglobin pulse oximetry (SpO2) below 90% at sea level. For the altitude adjustment, we use the same procedure described by Velasquez 8 . To determine the FiO2 in patients using conventional cannulas we use the approximation of Benaron (tidal volume [TV] of 6 ml/kg and an inspiratory time (IT) of 0.33 s) 8 .…”

Section: Methodsmentioning

confidence: 99%

“…For the altitude adjustment, we use the same procedure described by Velasquez 8 . To determine the FiO2 in patients using conventional cannulas we use the approximation of Benaron (tidal volume [TV] of 6 ml/kg and an inspiratory time (IT) of 0.33 s) 8 . All patients were treated following the recommendation about prevention, diagnosis, resuscitation, early management, and treatment of BPD established in the national guide for the management of the premature newborn 7,9 …”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Bronchopulmonary dysplasia: Incidence and severity in premature infants born at high altitude

Buendía

Ramírez_Velasquez

Benjumea-Bedoya

2021

Pediatric Pulmonology

View full text Add to dashboard Cite

Background Bronchopulmonary dysplasia (BPD) is the most common cause of chronic lung disease in children born prematurely. There is little information about the epidemiology and severity of BPD places with high altitude. This study aimed to evaluate the frequency of BPD severity levels and the associated risk factors with severity in a cohort of preterm newborns ≤36weeks of gestational age born in Rionegro, Colombia Materials and Methods We carried out a retrospective analytical cohort of preterm newborns without major malformations from Rionegro, Colombia between 2011 and 2018 admitted to neonatal intensive unit at high altitude (2200 m above sea level). The main outcomes were the incidence and severity of BPD. Results The BPD incidence was 23.5% 95% (confidence interval [CI], 19.6–27.7). BPD was grade 1 in 69.9%, grade 2 in 15.5% and grade 3 in 14.5% of patients. After modeling regression analysis, the final variables associated with BPD severity levels were: sepsis (odds ratio [OR], 4.15; 95% CI, 1.33–12.96) and pulmonary hypertension (OR: 3.86; 95% CI, 1.30‐11.4). Conclusion The incidence of BPD was higher and similar to cities with higher altitudes. In our population, the variables associated with BPD severity levels were: sepsis and pulmonary hypertension. It is necessary to increase the awareness of risk factors, the effect of clinical practices, and early recognition of BPD to reduce morbidity in patients with this pathology.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Bronchopulmonary dysplasia: Incidence and severity in premature infants born at high altitude

Buendía

Ramírez_Velasquez

Benjumea-Bedoya

2021

Pediatric Pulmonology

View full text Add to dashboard Cite

show abstract

“…For the severity classification, it was defined as mild if patient had no supplemental oxygen by week 36 PMA or discharge, moderate if patients had oxygen requirement of 0.29-0.41 by 36 weeks PMA or discharge, and it was defined as severe if the oxygen requirements were greater than 0.42 or if they required some kind of assisted ventilation. To determine the FiO2 in patients using conventional cannulas we use the approximation of Benaron (tidal volume [TV] of 6 ml/kg and an inspiratory time (IT) of 0.33 s) (8) All patients were treated following the recommendation about prevention, diagnosis, resuscitation, early management and treatment of bronchopulmonary dysplasia established in the national guide for the management of the premature newborn (10,11)…”

Section: Methodsmentioning

confidence: 99%

Bronchopulmonary dysplasia: incidence and severity in premature infants born at high altitude.

Rodriguez

Ramieez²,

Benjumea³

2021

Preprint

View full text Add to dashboard Cite

Background: Bronchopulmonary dysplasia (BPD) is the most common cause of chronic lung disease in children born prematurely. There is little information about the epidemiology and severity of BPD places with high altitude. This study aimed to evaluate the frequency of BPD severity levels and the associated risk factors with severity in a cohort of preterm newborns ≤34 weeks of gestational age born in Rionegro, Colombia Materials and methods: We carried out a retrospective analytical cohort of preterm newborns without major malformations from Rionegro, Colombia between 2011-2018 admitted to neonatal intensive unit at high altitude (2200m above sea level). The main outcomes were the incidence and severity of bronchopulmonary dysplasia. Results: The bronchopulmonary dysplasia incidence was 25.7% (95% CI, 21.6-29.9). Bronchopulmonary dysplasia was moderate in 62.1% of patients and severe in 26.7%. After modeling regression analysis, the final variables associated with BPD severity levels were: sepsis (OR 2.37 CI 95% 1.04-5.40) and pulmonary hypertension (OR 3.79 CI95% 1.19-12). Conclusion: The incidence of BPD was higher and similar to cities with higher altitudes. In our population, the variables associated with BPD severity levels were: duration of oxygen therapy and pulmonary hypertension. It is necessary to increase the awareness of risk factors, the effect of clinical practices, and early recognition of bronchopulmonary dysplasia to reduce morbidity in patients with this pathology.

show abstract

“…The diagnosis of bronchopulmonary dysplasia is frequently made on the basis of respiratory support at a specified age [12], which in turn is influenced by the goal oxygen saturation for a patient. Geographic factors, specifically altitude, can influence oxygen saturations and thus the prevalence of BPD [73][74][75]. A study of 561 preterm infants born in Utah within the Rocky Mountains found that correction for altitude reduced the rates of moderate-to-severe BPD by almost 50% [76].…”

Section: Altitudementioning

confidence: 99%

Influences of environmental exposures on preterm lung disease

Collaco¹,

Aoyama²,

Rice³

et al. 2021

Expert Review of Respiratory Medicine

View full text Add to dashboard Cite

Introduction: Environmental factors play a critical role in the progression or resolution of chronic respiratory diseases. However, studies are limited on the impact of environmental risk factors on individuals born prematurely with lung disease after they leave the neonatal intensive care unit and are discharged into the home environment. Areas covered:In this review, we cover current knowledge of environmental exposures that impact outcomes of preterm respiratory disease, including air pollution, infections, and disparities. The limited data do suggest that certain exposures should be avoided and there are potential preventative strategies for other exposures. There is a need for additional research outside the neonatal intensive care unit that focuses on individual and community-level factors that affect long-term outcomes.Expert opinion: Preterm respiratory disease can impose a significant burden on infants, children, and young adults born prematurely, but may improve for many individuals over time. In this review, we outline the exposures that may potentially hasten, delay, or prevent resolution of lung injury in preterm children.

show abstract

Bronchopulmonary dysplasia predictor scale validation in preterm newborns in two neonatal units at 2600 m above sea level

Cited by 6 publications

References 24 publications

Bronchopulmonary dysplasia: Incidence and severity in premature infants born at high altitude

Bronchopulmonary dysplasia: Incidence and severity in premature infants born at high altitude

Bronchopulmonary dysplasia: incidence and severity in premature infants born at high altitude.

Influences of environmental exposures on preterm lung disease

Contact Info

Product

Resources

About

Bronchopulmonary dysplasia predictor scale validation in preterm newborns in two neonatal units at 2600 m above sea level

Cited by 6 publications

References 24 publications

Bronchopulmonary dysplasia: Incidence and severity in premature infants born at high altitude

Bronchopulmonary dysplasia: Incidence and severity in premature infants born at high altitude

Bronchopulmonary dysplasia: incidence and severity in premature infants born at high altitude.

Influences of environmental exposures on preterm lung disease

Contact Info

Product

Resources

About

Bronchopulmonary dysplasia predictor scale validation in preterm newborns in two neonatal units at 2600 m above sea level