Bronchus-Associated Lymphoid Tissue (BALT) Lymphoma of the Lung Showing Mosaic Pattern of Inhomogeneous Attenuation on Thin-section CT: A Case Report

Lee, Injae; Kim, Sung Hwan; Koo, Soo Hyun; Kim, Hyun Beom; Hwang, Dae Hyun; Lee, Kwan Seop; Lee, Yul; Jang, Kee Taek; Kim, Duck-Hwan

doi:10.3348/kjr.2000.1.3.159

Cited by 18 publications

(15 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…MALT lymphoma (MALToma) is a monoclonal lymphoid proliferation arising from a B-cell progenitor within the BALT, and is classified as low-grade marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue in the World Health Organization classification (Table 6) (22,25,(39)(40)(41)(42)(43)(44)(45)(46)(47)(48). Histologically, MALT lymphoma is a lesion comprised of sheets of monoclonal lymphocytes with occasional interspersed plasma cells (22,25,41,43,46). These plasma cells often contain intranuclear inclusions of immunoglobulins known as Dutcher bodies.…”

Section: Malt Lymphomamentioning

confidence: 99%

“…CT shows multiple nodules, masses, and/or nodular/masslike areas of ground-glass attenuation or consolidation (or a mix of both), which tend to be in a bronchovascular distribution and often show air bronchograms (Figs 9-11). The air bronchograms within these lesions may be dilated (22,23,25,40,(42)(43)(44)46,47,49). More rarely, MALT lymphoma manifests as patchy large areas of ground-glass attenuation throughout the lungs (25,42,43,49).…”

Section: Malt Lymphomamentioning

confidence: 99%

See 1 more Smart Citation

Primary Pulmonary Lymphoid Lesions: Radiologic and Pathologic Findings

Sirajuddin¹,

Raparia²,

Lewis³

et al. 2016

RadioGraphics

106

View full text Add to dashboard Cite

The pulmonary lymphoid system is complex and is composed of two compartments: the pulmonary lymphatics and the bronchus-associated lymphoid tissue (BALT). Additional important cells that function in the pulmonary lymphoid system include dendritic cells, Langherhans cells, macrophages, and plasma cells. An appreciation of the normal lymphoid anatomy of the lung as well as its immunology is helpful in understanding the radiologic and pathologic findings of the primary pulmonary lymphoid lesions. Primary lymphoid lesions of the lung arise from the BALT and are uncommon. However, they are increasingly recognized within the growing number of posttransplant patients as well as other patients who are receiving immunosuppressive therapies. Primary lymphoid lesions encompass a wide range of benign and malignant lesions. Benign lymphoid lesions of the lung include reactive lymphoid hyperplasia, follicular bronchiolitis, lymphoid interstitial pneumonia, and nodular lymphoid hyperplasia. Malignant lymphoid lesions of the lung include low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT), other non-Hodgkin lymphomas, and Hodgkin lymphoma. Last, a miscellaneous group of primary lymphoid lesions includes lymphomatoid granulomatosis, posttransplant lymphoproliferative disorders, acquired immunodeficiency syndrome (AIDS)-related lymphoma, and intravascular lymphoma/lymphomatosis. These lesions are best evaluated with multidetector chest computed tomography. The radiologic findings of the primary lymphoid lesions are often nonspecific and are best interpreted in correlation with clinical data and pathologic findings. The purpose of this article is to review pulmonary lymphoid anatomy as well as the most common primary pulmonary lymphoid disorders.

show abstract

Section: Malt Lymphomamentioning

confidence: 99%

Section: Malt Lymphomamentioning

confidence: 99%

Primary Pulmonary Lymphoid Lesions: Radiologic and Pathologic Findings

Sirajuddin¹,

Raparia²,

Lewis³

et al. 2016

RadioGraphics

106

View full text Add to dashboard Cite

show abstract

“…These symptoms are mostly bilateral and multiple. 3,9,10 Diagnostic criteria for PPL are not certain and necessitate histological, immunohistochemical, and molecular biological findings. To evaluate the dispersion, upper and lower gastrointestinal endoscopy and bone marrow biopsy are essential.…”

Section: Discussionmentioning

confidence: 99%

“…[6][7][8][9] When lymphoma occurs in the lungs, factors such as smoking, autoimmune deficiencies, and infectious diseases are considered to correlate with the chronic antigenic stimulation of the disease. 1,[4][5][6]10,11 Primary pulmonary MALT lymphoma is most commonly seen between the 5th and 7th decades of life and rarely observed before 30 y of age. The disease occurrence has been thought to be similar in both sexes, but recent literature has reported a higher incidence in female patients.…”

Section: Introductionmentioning

confidence: 99%

Primary Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Accompanied by a Hydatid Cyst

et al. 2014

View full text Add to dashboard Cite

“…101,[104][105][106][107] Therefore, rigorous exclusion of lymphoma is required when lymphoid infiltrates are expansile or tumefactive and track along lymphangitic routes. Neoplasms of origins other than hematolymphoid can also occur.…”

Section: Pathologic Findingsmentioning

confidence: 99%

Pleuropulmonary Pathology in Patients With Rheumatic Disease

Schneider

Gruden

Tazelaar

et al. 2012

Archives of Pathology &Amp; Laboratory Medicine

View full text Add to dashboard Cite

Thoracic manifestations of rheumatic disease (RD) are increasingly recognized as a significant cause of morbidity and mortality worldwide. Rheumatologic underpinnings have been identified in a significant proportion of patients with interstitial lung disease. The 5 RDs most frequently associated with pleuropulmonary disease are (1) rheumatoid arthritis, (2) systemic lupus erythematosus, (3) progressive systemic sclerosis, (4) polymyositis/dermatomyositis, and (5) Sjögren syndrome. The onset of thoracic involvement in these diseases is variable. In some patients, it precedes the systemic disease or is its only manifestation. Moreover, there is a wide spectrum of clinical presentation ranging from subclinical abnormalities to acute respiratory failure. Histopathologically, the hallmark features of thoracic involvement by RD are inflammatory, targeting one or more lung compartments. The reactions range from acute to chronic, with remodeling by fibrosis being a common result. Although the inflammatory findings are often nonspecific, certain reactions or anatomic distributions may favor one RD over another, and occasionally, a distinctive histopathology may be present (eg, rheumatoid nodules). Three diagnostic dilemmas are encountered in patients with RD who develop diffuse lung disease: 1) opportunistic infection in the immunocompromised host, 2) drug toxicity related to the medications used to treat the systemic disease, and 3) manifestations of the patient's known systemic disease in lung and pleura. To confidently address the latter, the 5 major RDs are presented here, with their most common pleuropulmonary pathologic manifestations, accompanied by brief clinical and radiologic correlations.

show abstract

Bronchus-Associated Lymphoid Tissue (BALT) Lymphoma of the Lung Showing Mosaic Pattern of Inhomogeneous Attenuation on Thin-section CT: A Case Report

Cited by 18 publications

References 11 publications

Primary Pulmonary Lymphoid Lesions: Radiologic and Pathologic Findings

Primary Pulmonary Lymphoid Lesions: Radiologic and Pathologic Findings

Primary Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Accompanied by a Hydatid Cyst

Pleuropulmonary Pathology in Patients With Rheumatic Disease

Contact Info

Product

Resources

About