Brønsted acid-catalyzed cascade cyclization: an efficient strategy for divergent synthesis of cyclohepta[b]indole derivatives

Abstract

An efficient acid-catalyzed three-component cascade strategy was established on the basis of a crucial conversion of BIMs to vinylindoles, to synthesize a privileged scaffold, cyclohepta[b]indoles. The vinylindole intermediates worked as...

Increased catalytic activity through ZnMo7O24/g-C3N4 heterostructured assemblies for greener indole condensation reaction at room temperature

“…Although these methods have some advantages, most have fundamental weaknesses, such as harsh reaction conditions, volatile organic solvents, toxic reagents and solvents, limited substrate scope, expensive reagents, and catalyst overload. In recent years, the literature has also documented various green protocols, such as organocatalyst 20,21 , ionic liquids 22 , deep eutectic solvents 23 , ultrasounds 24 , and Taurine 25 for the efficient synthesis of indole derivatives.…”