Brown tumour of the spine in a renal transplant patient

Zaheer, S. Noman; Byrne, Stephen T.; Poonnoose, Santosh; Vrodos, Nikitas

doi:10.1016/j.jocn.2008.11.009

Cited by 13 publications

(6 citation statements)

References 7 publications

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“…[1] It is called BT because high hemosiderin level of localized accumulation of osteoclasts, fibrous tissue, and blood gives characteristic brown color. [2] The first case of primary hyperparathyroidism involving the spine was reported by Shaw and Davies[3] in 1968. BT is found in 3 and 1.5-1.7% of patients with primary and secondary hyperparathyroidism, respectively.…”

Section: Introductionmentioning

confidence: 99%

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Brown tumor as an unusual but preventable cause of spinal cord compression: Case report and review of the literature

et al. 2014

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Brown tumor (BT), also known as osteoclastoma, may appear in the context of primary and secondary hyperparathyroidism. Spinal cord compression due to the BT is extremely rare. We present here an unusual case of BT involving thoracal spine and mandible. A 26-year-old woman, who had been on hemodialysis for chronic renal failure for over 6 years, got admitted with dorsal pain and progressive weakness in her lower extremities and gait disturbances. Neurological examination revealed spastic paraparesis and symmetrically hyperactive tendon reflex in the lower extremities. She had hypoesthesia under T10 level. On physical examination, a swelling on the left side of her jaw was also detected. Magnetic resonance imaging (MRI) showed cord compression due to an extradural mass lesion at T8 level. A computerized tomography (CT) scan showed that this expansile lytic lesion was caused by the collapse of vertebra corpus (T8) at that level. CT of the mandible revealed an expansile lytic lesion on left arm of the mandible. Laboratory findings were nearly normal except parathormone level elevation to 1289 pg/mL (normal 30-70 pg/mL). Ultrasound examination showed enlargement of the parathyroid glands. The patient underwent an emergency decompression and stabilization surgery. The lesion was fragile and reddish in appearance and was easy to aspirate. The tumor was reported as “BT.” Her weakness in the lower extremities improved in the early postoperative period. Following surgical intervention, the patient was transferred to nephrology clinic for additional medical treatment.

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Section: Introductionmentioning

confidence: 99%

“…[1249] Multiple BT rarely is rarely found in a patient[101112] and it rarely locates in vertebra,[13] In this report, a case of a BT located in mandible and thoracal vertebra is presented with an extensive review of the literature.…”

Section: Introductionmentioning

confidence: 99%

Brown tumor as an unusual but preventable cause of spinal cord compression: Case report and review of the literature

et al. 2014

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“…18 They are called brown tumors due to the high hemosiderin level of localized accumulation of osteoclasts, vascularity and hemorrhage, that gives characteristic brown color. 19 These tumors arise secondary to both primary and secondary hyperparathyroidism. They have been reported to ocurr in 4,5% of patients with primary hyperparathyroidism and 1,5 to 1,7% of those with secondary disease.…”

Section: Discussionmentioning

confidence: 99%

Single-Step Primary Reconstruction After Complex Fronto-Orbital Brown Tumor Resection Using Computed-Designed Peek Implant

Laza¹,

González²,

González-García³

et al. 2016

Surg Res Open J

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The authors describe a patient with secondary hyperparathyroidism (HPT) who had development of a brown tumors (BTs) of the superior orbit and frontal calvarium with subsequent visual impairment. One-step surgery involving wide en-bloc resection of the entire tumor and immediate fronto-orbital reconstruction with a custom-made polyetheretherketone (PEEK) implant was planned. Using a PEEK implant a one-step reconstruction of the fronto-orbital region was achieved obtaining symmetry and good functional results, reducing operative time and avoiding donor site morbidity.

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“…[ 33 ] 2009 M/40 Secondary T9 body and pedicle Paraplegia Biopsy and surgical resection Noman Zaheer et al . [ 34 ] 2009 M/30 Secondary Thoracic Back pain and minimal neurological problem Surgical resection Kampschreur et al . [ 35 ] 2010 M/43 Secondary Thoracic Upper abdominal pain radiating to back Surgical resection and subtotal parathyroidectomy Gheith et al .…”

Section: Discussionmentioning

confidence: 99%