Brucella

Sriranganathan, Nammalwar; Seleem, Mohamed N.; Olsen, Steven C.; Samartino, Luis; Whatmore, Adrian M.; Bricker, Betsy J.; O’Callaghan, David; Halling, Shirley M.; Crasta, Oswald; Wattam, Alice R.; Purkayastha, Anjan; Sobral, Bruno W. S.; Snyder, Eric E.; Williams, Kelley P.; Yu, Gong-Xi; Ficht, Thomas A.; Roop, R. Martin; Figueiredo, Paul de; Boyle, Stephen M.; He, Yongqun; Tsolis, Renée M.

doi:10.1007/978-3-540-74042-1_1

Cited by 8 publications

(14 citation statements)

References 314 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The Tn 1953 , an 18kbp region discovered in the second chromosome of B. suis 1330, shows similarity with the anomalous region IncP. The Tn 1953 is also present in B. canis , B. neotomae , B. ceti, and B. pinnipedialis , but absent in B. melitensis , B. abortus, and B. ovis [ 155 ]. Among these IS, only IS 711 is considered a specific element of the Brucella genus and appears to be the only active transposable element in Brucella [ 155 , 156 ].…”

Section: Brucella Speciation and Host Preferencmentioning

confidence: 99%

“…The Tn 1953 is also present in B. canis , B. neotomae , B. ceti, and B. pinnipedialis , but absent in B. melitensis , B. abortus, and B. ovis [ 155 ]. Among these IS, only IS 711 is considered a specific element of the Brucella genus and appears to be the only active transposable element in Brucella [ 155 , 156 ]. The number and positions of IS 711 in the Brucella genomes ( Table 1 ) serve as a fingerprint for diagnosis and species identification [ 157 , 158 , 159 , 160 ].…”

Section: Brucella Speciation and Host Preferencmentioning

confidence: 99%

See 1 more Smart Citation

Brucella Genomics: Macro and Micro Evolution

Suárez-Esquivel

Chaves-Olarte

Moreno

et al. 2020

IJMS

View full text Add to dashboard Cite

Brucella organisms are responsible for one of the most widespread bacterial zoonoses, named brucellosis. The disease affects several species of animals, including humans. One of the most intriguing aspects of the brucellae is that the various species show a ~97% similarity at the genome level. Still, the distinct Brucella species display different host preferences, zoonotic risk, and virulence. After 133 years of research, there are many aspects of the Brucella biology that remain poorly understood, such as host adaptation and virulence mechanisms. A strategy to understand these characteristics focuses on the relationship between the genomic diversity and host preference of the various Brucella species. Pseudogenization, genome reduction, single nucleotide polymorphism variation, number of tandem repeats, and mobile genetic elements are unveiled markers for host adaptation and virulence. Understanding the mechanisms of genome variability in the Brucella genus is relevant to comprehend the emergence of pathogens.

show abstract

Section: Brucella Speciation and Host Preferencmentioning

confidence: 99%

Section: Brucella Speciation and Host Preferencmentioning

confidence: 99%

Brucella Genomics: Macro and Micro Evolution

Suárez-Esquivel

Chaves-Olarte

Moreno

et al. 2020

IJMS

View full text Add to dashboard Cite

show abstract

“…Brucellosis control is a political issue: farmers, dairy industry, animal health and human health authorities must work together to succeed (Sriranganathan et al., ), as proposed in the ‘One Health’ concept (Zinsstag et al., ). To implement this ‘One Health’ concept local actors should be involved more actively, such as the village physicians, who can be trained and equipped to run serological tests in humans.…”

Section: Discussionmentioning

confidence: 99%

“…is the most common zoonotic infection spread worldwide (Pappas et al., ). Eight species of Brucella are identified (Sriranganathan et al., ). The most common pathogens in decreasing order of their incidence in humans are B. melitensis (small ruminants), B. suis (pigs) and B. abortus (cattle) (Lucero et al., ).…”

Section: Introductionmentioning

confidence: 99%

‘La fiebre de Malta’: An Interface of Farmers and Caprine Brucellosis Control Policies in the Bajío Region, Mexico

Montiel

Udo

Frankena

et al. 2015

Transbound Emerg Dis

View full text Add to dashboard Cite

This article shows that socio-economic factors, defined here as practices, knowledge, interests, beliefs and experiences have a role in the adoption of brucellosis control strategies in the Bajío region, Mexico. We combined qualitative and quantitative methods to show that socio-economic factors with regard to goat husbandry and brucellosis control are not taken into account in the current policy to combat the disease in Mexico. Farmers ranked constraints like the price of goat milk more important than the control of the disease. The impact of brucellosis in goats is hidden to farmers, and the term brucellosis is still a strange name to them; it is better known as 'la fiebre de Malta' (Malta fever), which farmers are aware of and which they avoid by not drinking goat milk. Brucellosis control measures cause losses such as abortion due to vaccination and ear infections due to ear tagging. In the villages of the state of Michoacán, the uptake of a vaccination and testing programme was almost complete because it was offered for free, whereas in villages of Jalisco, vaccination was not adopted thoroughly because the cost of vaccination was high for farmers and because of a lack of veterinarians offering the service. Neither compensation for culling suspected infected goats does exist nor the infrastructure, like slaughterhouses, to ensure that goats that are brucellosis seropositive are not resold to neighbouring farmers. This article disputes the idea that brucellosis is confined to the lack of awareness and participation of farmers in control measures, but rather that policies are promulgated without a good knowledge of goat husbandry and farmers' perceptions. We claim that governmental authorities should reformulate the policy to take into account socio-economic factors shaping farmers' behaviour so that effective control measures will be adopted by goat farmers.

show abstract

“…The genomes of all Brucella species are having similar size and genome atlas (Sriranganathan et al 2009 ), with average genome size of approximately 3.29 Mb consisting of two circular chromosomes. Chromosome I is approximately 2.11 Mb and chromosome II is about 1.18 Mb.…”

Section: The Bacteriummentioning

confidence: 99%

Bovine brucellosis – a comprehensive review

Khurana

Sehrawat

Tiwari

et al. 2021

Veterinary Quarterly

155

View full text Add to dashboard Cite

Brucellosis is a zoonotic disease of great animal welfare and economic implications worldwide known since ancient times. The emergence of brucellosis in new areas as well as transmission of brucellosis from wild and domestic animals is of great significance in terms of new epidemiological dimensions. Brucellosis poses a major public health threat by the consumption of non-pasteurized milk and milk products produced by unhygienic dairy farms in endemic areas. Regular and meticulous surveillance is essentially required to determine the true picture of brucellosis especially in areas with continuous high prevalence. Additionally, international migration of humans, animals and trade of animal products has created a challenge for disease spread and diagnosis in non-endemic areas. Isolation and identification remain the gold standard test, which requires expertise. The advancement in diagnostic strategies coupled with screening of newly introduced animals is warranted to control the disease. Of note, the diagnostic value of miRNAs for appropriate detection of B. abortus infection has been shown. The most widely used vaccine strains to protect against Brucella infection and related abortions in cattle are strain 19 and RB51. Moreover, it is very important to note that no vaccine, which is highly protective, safe and effective is available either for bovines or human beings. Research results encourage the use of bacteriophage lysates in treatment of bovine brucellosis. One Health approach can aid in control of this disease, both in animals and man.

show abstract

Brucella

Cited by 8 publications

References 314 publications

Brucella Genomics: Macro and Micro Evolution

Brucella Genomics: Macro and Micro Evolution

‘La fiebre de Malta’: An Interface of Farmers and Caprine Brucellosis Control Policies in the Bajío Region, Mexico

Bovine brucellosis – a comprehensive review

Contact Info

Product

Resources

About