Brucella Endocarditis: The Importance of Surgical Timing After Medical Treatment (Five Cases)

Özsöyler, İbrahim; Yilik, Levent; Bozok, Şahin; El, Sibel; Emrecan, Bilgin; Biceroglu, Serdar; Gürbüz, Ali

doi:10.1016/j.pcad.2004.10.001

Cited by 16 publications

(10 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Control of infection with preoperative antibiotic therapy and immediate surgery after clinical stabilization has also been recommended [30]. The intracellular location of the microorganism makes it inaccessible to the action of many antibiotics [31].…”

Section: Commentmentioning

confidence: 99%

Medical Versus Medical and Surgical Treatment for Brucella Endocarditis

Keshtkar-Jahromi

Razavi

Gholamin

et al. 2012

The Annals of Thoracic Surgery

View full text Add to dashboard Cite

This review was undertaken to determine the role of surgery in the treatment of brucella endocarditis. All English and French articles reporting brucella endocarditis (1966–2011) in Pubmed, Google and Scopus were reviewed. 308 cases were identified and Linear and Logistic regression was performed. Surgery improved outcomes by decreasing mortality from 32.7% in the medical treatment only group to 6.7% in the combined surgical and medical treatment group (p<.001). This association was still significant while controlling for other contributing factors. In the absence of a controlled trial, we recommend the utmost vigilance and consideration of surgical management in treating such patients.

show abstract

Section: Commentmentioning

confidence: 99%

Medical Versus Medical and Surgical Treatment for Brucella Endocarditis

Keshtkar-Jahromi

Razavi

Gholamin

et al. 2012

The Annals of Thoracic Surgery

View full text Add to dashboard Cite

show abstract

“…4 The morbidity and mortality associated with BE can be reduced with adequate medical and surgical approach. 5 We report the management of 31 cases of native BE with combined medical and surgical therapy. Between 1996 and2007, 18 male and 13 female patients, ranging between 22 and 69 years, with BE were admitted to Ankara University School of Medicine.…”

Section: Introductionmentioning

confidence: 99%

Native Valve Brucella Endocarditis

İnan

Eyileten

Özçınar

et al. 2010

Clinical Cardiology

View full text Add to dashboard Cite

Objective: Brucellosis is frequently seen in Mediterranean and Middle East countries, including Turkey. We report the medical and surgical management of 31 cases of native endocarditis. Material and Method: Thirty-one patients were admitted to our clinic with suspected Brucella Endocarditis. The diagnosis was established by either isolation of Brucella species, or the presence of antibodies. Following preoperative antibiotic therapy patients underwent valve replacement with excessive tissue debridment. Patients were followed up with Brucella titers, blood cultures, and echocardiography. Results: On admission all patients were febrile and mostly dyspneic (NYHA Class 3 or 4). The blood tests were normal except for elevated ESR, CRP and serological tests. The aortic valve was involved in 19 patients, mitral valve in 7 patients, and both valves in 5. After serological confirmation of BE, antibiotic therapy was maintained. Twenty-five of the patients received rifampicine, doxycycline, and cotrimaxozole; 2 of them received a combination of rifampicine, streptomycin, and doxycycline; and 4 of them received rifampicine, tetracycline, and cotrimaxozole. Tissue loss in most of the affected leaflets and vegetationswere presenting all patients. Valve replacements were performed with mechanical and biologic prostheses. All the patients were afebrile at discharge but received the antibiotics for 101, 2 ± 16, 9 days. The follow-up was 37, 1 ± 9, 2 months. Discussion: In our retrospective study, combination of adequate medical and surgical therapy resulted in declined morbidity and mortality rate. The valve replacement with aggressive debridement is the most important part of the treatment, which should be supported with efficient preoperative and long term postoperative medical treatment.

show abstract

“…3,6,8 Antibiotic therapy followed by surgery seems to be the most effective treatment. 1,4,6,7 In the present patient the surgical and medical treatment were performed together.…”

Section: Discussionmentioning

confidence: 90%

Brucellosis with p-ANCA-associated renal failure, leukocytoclastic vasculitis and endocarditis: Case report

Turgay¹

2011

JMID

View full text Add to dashboard Cite

The relationship between brucellosis and p-antinuclear cytoplasmic antibody (p-ANCA)-associated vasculitis (pAAV) is a rare condition. Herein, we report a 52-year-old man who was diagnosed as rapidly progressive glomerulonephritis (RPGN) and endocarditis due to brucellosis. He was treated with antimicrobial agents, steroids, plasmapheresis, renal replacement therapy and aortic valve replacement. According to our best of knowledge, no similar case has been reported previously in the literature in regard to p-ANCA anti-lactoferrin antibodies associated-glomerulonephritis with brucellosis and endocarditis.

show abstract

Brucella Endocarditis: The Importance of Surgical Timing After Medical Treatment (Five Cases)

Cited by 16 publications

References 5 publications

Medical Versus Medical and Surgical Treatment for Brucella Endocarditis

Medical Versus Medical and Surgical Treatment for Brucella Endocarditis

Native Valve Brucella Endocarditis

Brucellosis with p-ANCA-associated renal failure, leukocytoclastic vasculitis and endocarditis: Case report

Contact Info

Product

Resources

About