Brucella prostatic abscess: a retrospective study of eight cases and a literature review

Lan, Siqin; Guo, Zhaoxing; He, Yuanlin; Liu, Wenya; Guo, Hui

doi:10.1177/03000605211027442

Cited by 1 publication

(1 citation statement)

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“…In order to achieve this goal, the investigation conducted an extensive analysis of the patients’ medical history, comorbidities, therapeutic interventions, and clinical outcomes. The findings of this study carry substantial implications for clinical practice, furnishing crucial insights that can guide medical professionals in developing personalized treatment plans for patients afflicted with PA [ 11 , 12 , 13 , 14 ]. The results of this research have the potential to significantly enhance patient outcomes and, as a result, elevate the quality of care provided to individuals grappling with this condition.…”

Section: Introductionmentioning

confidence: 99%

Factors Deciding Conservative or Intervention Treatment for Prostate Abscess: A Retrospective Case-Control Study

Chang

Pan

Lin

et al. 2023

JPM

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Prostate abscess (PA) can lead to severe urosepsis and septic shock if not treated promptly. However, early diagnosis can be hindered by the declining incidence of PA, especially in developing countries and high-risk patients. Despite the prevalence of PA, there is currently a lack of well-established contemporary guidelines or treatment algorithms. This study aimed to review the etiology, pathophysiology, diagnosis, and treatment options for PA, as well as analyze the characteristics, background profiles of patients, and clinical course. Ultimately, the goal was to develop a personalized treatment strategy for patients with PA. This retrospective study examined 44 patients diagnosed with PA at a tertiary medical center between 2010 and 2020. The patients were divided into two groups based on their treatment: conservative treatment or intervention (transurethral resection of the prostate [TURP] or transurethral prostate drainage [TPD]). The study evaluated various factors, including patients’ background profiles, comorbidities, laboratory data, and PA size and volume. Complications of the interventions were also analyzed. No significant differences were found in basic data between the conservative treatment group (19 patients) and intervention group (25 patients; 20 for TURP, 5 for TPD). However, it was observed that single abscesses, size <2.2 cm, and prostate volume <48 cm3, may be suitable for conservative treatment. Patients with diabetes mellitus and human immunodeficiency virus should be monitored for thrombotic events. In addition, there was a significant difference in white blood count between the two groups (12.1 ± 7.0 vs. 17.6 ± 9.7 × 109/L, p < 0.05). A subgroup analysis of the intervention group showed no significant difference in the risk of complications between TPD and TURP. Patients with poorly controlled diabetes mellitus and immunodeficiency are at a high risk of PA but are not indicated for surgical treatment. The PA profile, including number, size, volume, and percentage to prostate volume, should be considered when deciding on surgical intervention for patients with PA. Patients with higher leukocytosis may require surgical treatment. Overall, these findings can help guide the development of a personalized treatment strategy for patients with PA.

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