Brucellar arthritis in children and its successful treatment with trimethoprim-sulphamethoxazole (co-trimoxazole).

Abstract

SUMMARYThe clinical characteristics and the response to treatment with high doses of co-trimoxazole in 12 children with brucellar arthritis were analysed retrospectively. The children lived in an urban area and all but two had a history of unprocessed milk or cheese ingestion. Fever and oligoarthritis of the lower extremities were the most common clinical findings. Control of the disease was achieved by three months of treatment. Compliance with the medication was excellent, and no significant side effects occurred.

Brucella arthritis: a study of 96 cases in Kuwait.

“…Plain radiographs showed no major pathological changes. [13][14][15][16][17][18][19]. Clinical responsesubsidence of fever and arthralgia-was seen in most patients after three to eight days of treatment.…”

Brucellar arthritis of knee in a child

“…have stated that a subacute presentation with oligoarthritis predominantly affecting the hips and knees is common 6 . Gomez‐Reino has also stated that fever and oligoarthritis of lower extremities are the most common clinical findings 7 . In another study monoarthritis has been noticed in 45% of patients with brucellosis 8 .…”

Manifestations articulaires de la brucellose

“…L'atteinte articulaire périphérique est la règle chez l'enfant [21,22] et dans la brucellose liée à B. abortus [23]. Il a été rapporté chez l'enfant une monoarthrite du genou due à B. canis [24].…”

“…À l'inverse, l'atteinte sacro-iliaque est rare chez l'enfant [21,22] et lors des infections à B. abortus ou à B. suis [33]. Les adultes jeunes ont un risque particulier à développer une sacro-iliite lors d'une brucellose [26,31].…”

“…Elle semble rare chez l'enfant [21,22,34]. Elle a été rapportée de manière occasionnelle lors d'infections à B. abortus et B. suis [33,40,41], avec des caractéristiques cliniques semblables à celles observées avec B. melitensis.…”