Ischaemia: case reportA 56-year-old man developed ischaemia during treatment with dipyridamole for minimal exertion angina. The man with a history of dyslipidaemia and hypertension, underwent a neurosurgical preoperative evaluation (spinal arachnoid cyst). He presented to the emergency department with a 3-week history of minimal exertion angina. An ECG on admission showed nonspecific ST-T changes in the inferior leads and a type-2 Brugada ECG pattern in leads V1-V2. He received IV infusion of dipyridamole 0.56 mg/kg. Three minutes after ending intravenous infusion of dipyridamole, a type-1 Brugada ECG pat-tern was recorded in leads V1-V2, associated with ECG evidence of ischaemia.The man received treatment with aminophylline. The type-1 Brugada ECG pattern resolved and electrical evidence of ischaemia normalised after aminophylline administration. Gated-single photon emission CT images showed severe and extensive inferior ischaemia induced by pharmacological stress. A coronary angiogram detected a subacute thrombotic occlusion in the proximal right coronary artery (RCA) and severe proximal stenosis of a left circumflex artery that was distally occluded. Due to large ischaemic burden, a percutaneous coronary stenting of proximal and mid RCA was performed. A repeat ECG after coronary intervention showed the same QRS-T morphology as seen at the time of admission. He was discharged after 48h without any complication.