Buccal mucosa graft repair of proximal ureteral lesion

Proietti, F.; Brassetti, Aldo; Mirabile, Gabriella; Pansadoro, A.; Giandotti, M.; Martini, M.; Emiliozzi, P.; Pansadoro, V.

doi:10.1016/s0302-2838(21)01653-5

Cited by 1 publication

(3 citation statements)

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“…Finally, 23 studies with a total of 825 patients met the eligibility criteria for our meta‐analysis [11–18,22–36]. A total of 13 studies with 607 patients presented their experience with IUR, and 10 studies with 218 patients described OMGU for the treatment of ureteric stricture (Table 1) [11–18,22–36]. The median (range) sample size per study was 19 (9–108).…”

Section: Resultsmentioning

confidence: 99%

“…A total of 4031 references were identified for the initial search. After removing duplicate references and screening the Finally, 23 studies with a total of 825 patients met the eligibility criteria for our meta-analysis [11][12][13][14][15][16][17][18][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36]. A total of 13 studies with 607 patients presented their experience with IUR, and 10 studies with 218 patients described OMGU for the treatment of ureteric stricture (Table 1) [11][12][13][14][15][16][17][18][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36].…”

Section: Search Resultsmentioning

confidence: 99%

“…The traditional management of long proximal and middle ureteric strictures was IUR in the past, but it had some inherent limitations, such as large surgical trauma and considerable postoperative complications [26,30,32]. As urethral reconstruction with OMGs was used to restore the patency of urethra [37], it has been internationally recognised and OMGU was developed based on it [11,12,24,35]. It is known that the OMGs are ideal tissue for ureteric reconstruction with the advantages of easy harvesting and rich vessels, which favours the survival of grafts [35].…”

Section: Discussionmentioning

confidence: 99%

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Oral mucosal graft ureteroplasty versus ileal ureteric replacement: a meta‐analysis

et al. 2023

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ObjectivesTo describe outcomes of oral mucosal graft ureteroplasty (OMGU) and ileal ureter replacement (IUR) and determine the relative merits of both procedures. MethodsDatabases (including PubMed, Embase and Cochrane) were interrogated for eligible trials that assessed outcomes of OMGU or IUR from 2000 to 30 July 2022. The variables analysed were reconstruction success rates, stricture length, hospital stays, perioperative complications and long-term complications. ResultsA total of 23 single-arm studies were included. The pooled reconstruction success rates for OMGU and IUR were 94.9% (95% confidence interval [CI] 91.0%-97.7%) and 85.8% (95% CI 81.0%-90.0%), respectively. Stricture length of patients in the OMGU and IUR groups were 3.73 (95% CI 3.17-4.28) and 11.55 (95% CI 9.82-13.29) cm, respectively. The maximal stricture length repaired by OMGU was 8 cm. The hospital stays were 5.85 (95% CI 3.88-7.82) and 11.55 (95% CI 6.93-16.17) days in the OMGU and IUR groups, respectively. The incidences of low-grade postoperative complications were 13.6% (95% CI 6.9%-20.3%) and 27.3% (95% CI 19.5%-35.1%), high-grade postoperative complications were 4.6% (95% CI 1.8I-8.5%) and 13.0% (95% CI 9.4%-17.1%), and long-term complications (occurred at > 3months) were 9.0% (95% CI 1.7%-20.0%) and 35.4% (95% CI 25.8%-45.6%) in the OMGU and IUR groups, respectively. ConclusionAn OMGU is an effective, minimally invasive, and safe alternative to IUR for the management of long ureteric strictures. OMGU was the preferred treatment for long ureteric strictures, especially obstructed ureter segments of ≤8 cm.

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Section: Resultsmentioning

confidence: 99%