Budd–Chiari Syndrome Management: Controversies and Open Issues

Mancuso, Andrea

doi:10.3390/diagnostics12112670

Cited by 6 publications

(6 citation statements)

References 75 publications

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“…Otras complicaciones son sangrados y trombosis en otros órganos. Se han documentado casos de carcinoma hepatocelular derivado del SBC; sin embargo, esta presentación es muy rara, con un riesgo absoluto de 0.6% a 5 años después del diagnóstico de SBC (10,11).…”

Section: Complicacionesunclassified

Síndrome de Budd-Chiari: abordaje y manejo

Pérez¹,

Barquero²,

Mata³

2023

Rev.méd.sinerg.

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El síndrome de Budd-Chiari se cataloga dentro de las enfermedades poco frecuentes, con una incidencia de 0.45 por cada millón de personas. Consiste en una obstrucción al flujo venoso hepático que obedece a múltiples etiologías, más comúnmente a una trombosis venosa, generando una congestión hepática con aumento de presión venosa portal, produciendo así fibrosis y eventualmente falla hepática. Su manejo se orienta en revertir la obstrucción, mejorado el flujo sanguíneo y la perfusión para preservar la función del órgano.

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Section: Complicacionesunclassified

Síndrome de Budd-Chiari: abordaje y manejo

Pérez¹,

Barquero²,

Mata³

2023

Rev.méd.sinerg.

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“…The underlying disease may develop negatively in about 10% of cases, as is the case for prothrombotic factors, thus affecting the prognosis of BCS. Additional concerns are bleeding and thrombosis of other organs [21]. Although commendable efforts have been made to establish the background of diagnostic methods for BCS, there are currently no universal diagnostic criteria.…”

Section: Diffuse Liver Diseasesmentioning

confidence: 99%

Radiobioinformatics: A novel bridge between basic research and clinical practice for clinical decision support in diffuse liver diseases

Lei

et al. 2023

iRADIOLOGY

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The liver is a multifaceted organ that is responsible for many critical functions encompassing amino acid, carbohydrate, and lipid metabolism, all of which make a healthy liver essential for the human body. Contemporary imaging methodologies have remarkable diagnostic accuracy in discerning focal liver lesions; however, a comprehensive understanding of diffuse liver diseases is a requisite for radiologists to accurately diagnose or predict the progression of such lesions within clinical contexts. Nonetheless, the conventional attributes of radiological features, including morphology, size, margin, density, signal intensity, and echoes, limit their clinical utility. Radiomics is a widely used approach that is characterized by the extraction of copious image features from radiographic depictions, which gives it considerable potential in addressing this limitation. It is worth noting that functional or molecular alterations occur significantly prior to the morphological shifts discernible by imaging modalities. Consequently, the explication of potential mechanisms by multiomics analyses (encompassing genomics, epigenomics, transcriptomics, proteomics, and metabolomics) is essential for investigating putative signal pathway regulations from a radiological viewpoint. In this review, we elaborate on the principal pathological categorizations of diffuse liver diseases, the evaluation of multiomics approaches pertaining to diffuse liver diseases, and the prospective value of predictive models. Accordingly, the overarching objective of this review is to scrutinize the interrelations between radiological features and bioinformatics as well as to consider the development of prediction models predicated on radiobioinformatics as integral components of clinical decision support systems for diffuse liver diseases.

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“…Co więcej, krwawienie związane z zabiegiem stanowi poważne ryzyko, przez już występujące przekrwienie wątroby, jak i leczenie przeciwzakrzepowe. Jednak w wybranych przypadkach zalety TIPS przewyższają potencjalne ryzyko [17]. TIPS daje dobre rezultaty, szczególnie przy zastosowaniu nowoczesnych, pokrytych politetrafluoroetylenem (ePTFE) stentów.…”

Section: Leczenieunclassified

“…Jednak SSPCS nie ma zastosowania w przypadku zakrzepicy IVC, w przypadku której SSPCS + zespolenie systemowo-przedsionkowe (ang. CAS cavoatrial shunt) lub zastąpienie niedrożnego odcinka IVC homograftem żyły głównej, są preferowanymi metodami [17].…”

Section: Leczenieunclassified

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Budd-Chiari Syndrome - classification, diagnostics, imaging and treatment

Rybkowska

Żuchnik

Licak

et al. 2023

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Introduction: Budd-Chiari syndrome is a rare condition which can be defined as hepatic venous outflow obstruction occurring at any level between the small hepatic veins and junction of the inferior vena cava and the right atrium. Symptoms may vary from mild or even asymptomatic for many years to fulminant hepatic failure. Imaging is the mainstay of diagnosis of BCS. Laboratory and ematological tests are invaluable in recognizing hematological and coagulation disorders that may be identified in up to 75% of the patients. The recommended therapeutic approach to BCS is based on a stepwise algorithm beginning with medical treatment, endovascular treatment to restore vessel patency, placement of transjugular portosystemic shunt (TIPS), and orthotopic liver transplantation as a last resort rescue treatment. The aim of the study: This study aims to gather current knowledge about clinical manifestations, diagnosis and treatment of Budd-Chiari syndrome. Materials and methods: This review was based on available data collected in the PubMed database and Google Scholar web search engine, using the keywords: ’Budd-Chiari syndrome’ ,’hepatic venous outflow obstruction’. Conclusions: The treatment of Budd-Chiari syndrome requires interdisciplinary cooperation, which has resulted in the increasing curability of this rare disease over the last years.

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Budd–Chiari Syndrome Management: Controversies and Open Issues

Abstract: Budd–Chiari Syndrome (BCS) is due to thrombosis of hepatic veins (HVs), inferior vena cava (IVC) or both, leading to impaired hepatic venous outflow [...]

Cited by 6 publications

References 75 publications

Síndrome de Budd-Chiari: abordaje y manejo

Síndrome de Budd-Chiari: abordaje y manejo

Radiobioinformatics: A novel bridge between basic research and clinical practice for clinical decision support in diffuse liver diseases

Budd-Chiari Syndrome - classification, diagnostics, imaging and treatment

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