Building a bionic nervous system

Denison, Timothy; Morris, Milton D.; Sun, Felice T.

doi:10.1109/mspec.2015.7024509

Cited by 27 publications

(21 citation statements)

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“…One of the applications of intrabody nanonetworks has been the monitoring of the human nervous system. Communication with nanomachines implanted in the living human brain has already been used in the treatment for drug-resistant epilepsy [210]. In [211], a nanoscale stimulator device called synaptic nanomachine (SnM) was presented, which had effects on the synchronization of neurons and their oscillatory behaviors.…”

Section: Ibc In Medicinementioning

confidence: 99%

Past Results, Present Trends, and Future Challenges in Intrabody Communication

Naranjo-Hernández

Callejón-Leblic

Vasić

et al. 2018

Wireless Communications and Mobile Computing

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Intrabody communication (IBC) is a wireless communication technology using the human body to develop body area networks (BANs) for remote and ubiquitous monitoring. IBC uses living tissues as a transmission medium, achieving power-saving and miniaturized transceivers, making communications more robust against external interference and attacks on the privacy of transmitted data. Due to these advantages, IBC has been included as a third physical layer in the IEEE 802.15.6 standard for wireless body area networks (WBANs) designated as Human Body Communication (HBC). Further research is needed to compare both methods depending on the characteristics of IBC application. Challenges remain for an optimal deployment of IBC technology, such as the effect of long-term use in the human body, communication optimization through more realistic models, the influence of both anthropometric characteristics and the subject's movement on the transmission performance, standardization of communications, and development of small-size and energy-efficient prototypes with increased data rate. The purpose of this work is to provide an indepth overview of recent advances and future challenges in human body/intrabody communication for wireless communications and mobile computing.

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Section: Ibc In Medicinementioning

confidence: 99%

Past Results, Present Trends, and Future Challenges in Intrabody Communication

Naranjo-Hernández

Callejón-Leblic

Vasić

et al. 2018

Wireless Communications and Mobile Computing

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“…The integration of signal processing with neurophysiological sensing and actuation enables real-time online control strategies toward realizing adaptive, autonomous closed-loop systems for remediation of neurological disorders [107], [108]. Online signal processing of ECoG data has tremendous potential to improve patient outcomes in diseases currently lacking therapy or requiring resection of otherwise healthy neural tissue such as intractable epilepsy.…”

Section: E Integrated Electrocortical Online Data Processingmentioning

confidence: 99%

Silicon-Integrated High-Density Electrocortical Interfaces

Akinin

Park

et al. 2017

Proc. IEEE

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“…This is nowhere more clear than for closed-loop neuromodulation therapies that drive stimulation or update stimulation parameters based on information obtained from detected biopotentials [1]. These types of systems hold potential to drastically improve the efficacy of open-loop neuromodulation, in applications such as deep-brain stimulation for Parkinson’s disease [2] and cortical stimulation for epilepsy [3].…”

Section: Introductionmentioning

confidence: 99%

A Bidirectional Neural Interface IC With Chopper Stabilized BioADC Array and Charge Balanced Stimulator

Greenwald

Wang

et al. 2016

IEEE Trans. Biomed. Circuits Syst.

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We present a bidirectional neural interface with a 4-channel biopotential analog-to-digital converter (bioADC) and a 4-channel current-mode stimulator in 180nm CMOS. The bioADC directly transduces microvolt biopotentials into a digital representation without a voltage-amplification stage. Each bioADC channel comprises a continuous-time first-order ΔΣ modulator with a chopper-stabilized OTA input and current feedback, followed by a second-order comb-filter decimator with programmable oversampling ratio. Each stimulator channel contains two independent digital-to-analog converters for anodic and cathodic current generation. A shared calibration circuit matches the amplitude of the anodic and cathodic currents for charge balancing. Powered from a 1.5V supply, the analog and digital circuits in each recording channel draw on average 1.54 μA and 2.13 μA of supply current, respectively. The bioADCs achieve an SNR of 58 dB and a SFDR of >70 dB, for better than 9-b ENOB. Intracranial EEG recordings from an anesthetized rat are shown and compared to simultaneous recordings from a commercial reference system to validate performance in-vivo. Additionally, we demonstrate bidirectional operation by recording cardiac modulation induced through vagus nerve stimulation, and closed-loop control of cardiac rhythm. The micropower operation, direct digital readout, and integration of electrical stimulation circuits make this interface ideally suited for closed-loop neuromodulation applications.

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Building a bionic nervous system

Cited by 27 publications

References 0 publications

Past Results, Present Trends, and Future Challenges in Intrabody Communication

Past Results, Present Trends, and Future Challenges in Intrabody Communication

Silicon-Integrated High-Density Electrocortical Interfaces

A Bidirectional Neural Interface IC With Chopper Stabilized BioADC Array and Charge Balanced Stimulator

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