Building a bridge from the swamp to the ivory tower: Conducting randomised controlled trials in general practice

Heal, Clare; Banks, Jennifer; Divakaran, Pranav; Büttner, Petra

doi:10.31128/afp-09-17-4347

Cited by 3 publications

(6 citation statements)

References 16 publications

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“…Despite these significant strengths, a trial of this nature comes with methodological challenges. Recruitment across 20 geographically dispersed sites could prove challenging given the well reported engagement, recruitment and retention issues associated with multi-center RCTs in primary care (Heal et al, 2018). Therefore, there is potential that predicted sample size may not be achieved.…”

Section: Previous Interventions Have Employed Evidence Based Strategimentioning

confidence: 99%

“…While research in general practice is necessary to improve service delivery and enhance evidence based patient care, barriers to participation have been identified. The Australian fee-for-service system, time pressures and poor financial incentives for research activities are regularly cited factors that influence participation refusal (Brodaty et al, 2013, Heal et al, 2018, McKinn et al, 2015. In an effort to overcome these barriers, ImPress has been designed to ensure that minimal financial, time and workload burdens are associated with intervention implementation and delivery.…”

Section: Previous Interventions Have Employed Evidence Based Strategimentioning

confidence: 99%

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Improving blood pressure control in primary care: The ImPress study

Stephen

Halcomb

McInnes

et al. 2019

International Journal of Nursing Studies

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Section: Previous Interventions Have Employed Evidence Based Strategimentioning

confidence: 99%

Section: Previous Interventions Have Employed Evidence Based Strategimentioning

confidence: 99%

Improving blood pressure control in primary care: The ImPress study

Stephen

Halcomb

McInnes

et al. 2019

International Journal of Nursing Studies

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“…Members of the study team have conducted multiple randomised controlled trials (RCTs) on skin excisions in the North Queensland region. [22][23][24] Study design This is a prospective RCT. The intervention group will have grafts secured with fibrin glue applied across the entire graft bed (figure 1).…”

Section: Methods and Analysis Study Centrementioning

confidence: 99%

Protocol for an open randomised controlled trial investigating Fibrin Glue in Skin grafts for Skin cancer (FiGSS)

Paw

Vangaveti²,

Zonta³

et al. 2022

BMJ Open

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IntroductionSkin cancer is a common disease in the tropics, and oncological resection typically requires reconstruction with skin grafts. Fibrin glue, initially established as a haemostatic agent, has been studied extensively as an adhesive for skin grafts in burns. This study aims to investigate the use of fibrin as an adhesive for split skin grafts in skin cancers.Methods and analysisThe study design is a prospective randomised controlled trial with the aim of investigating the impact of two different methods of split skin graft fixation. The intervention of fibrin glue will be compared with the control of staples or sutures. The trial will be conducted at two sites, a public hospital and a private hospital in Townsville, Australia, over a 24-month period with 334 participants to be recruited. Consecutive patients presenting for skin excisions and grafting will be eligible to participate in this study. Randomisation will be on the level of the patient. The primary outcome is graft take based on wound healing at 1 month. Secondary outcomes will be pain on dressing changes and operative time.Ethics and disseminationThe study has been approved by The Townsville University Hospital Human Research Ethics Committee. Findings will be disseminated in conference presentations and journals and through online electronic media.Trial registration numberACTRN12618000484246.

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“…1,2 While 85% of the Australian population visit their GPs annually, general practice research is underrepresented in the amount of research funding it receives when compared with tertiary healthcare settings. 1,3 Research conducted in tertiary care may not generate findings applicable to general practice patients. 1,[4][5][6] However, it is crucial that clinical practice be informed by general practice research so that GPs have tools and guidelines appropriate for their patients.…”

mentioning

confidence: 99%

“…1,[4][5][6] However, it is crucial that clinical practice be informed by general practice research so that GPs have tools and guidelines appropriate for their patients. 3,7 Barriers and enablers to conducting general practice research have been documented; 8 these barriers can be overcome through collaboration with academic departments and larger centres, particularly for larger studies. 9 Research about issues that GPs consider to be of clinical importance, and those that their patients consider to be relevant, is more likely to succeed.…”

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confidence: 99%

General practice research priority setting in Australia: Informing a research agenda to deliver best patient care

Heal¹,

Roberts²

2019

Aust J Gen Pract

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Background General practice research is the subsection of primary care research that addresses gaps in evidence about care delivered in general practice. Despite delivering care to 85% of the Australian population annually, general practice receives a paucity of government health research funding when compared with tertiary healthcare settings. However, general practitioners (GPs) require evidence-based tools and guidelines applicable to their patients. Objective The aim of this study was to establish a set of general practice research priorities to guide resource allocation, and to inform a research agenda that optimises the delivery of the best patient care. Method A comprehensive literature review was conducted, followed by a modified two-round Delphi survey of general practice stakeholders. Results Sixty-seven general practice research priorities were identified. Priorities included quality care and evidencebased practice. Discussion The results provide a contemporary reference point for an Australian general practice research agenda that helps prioritise and advocate for funding, and enables delivery of evidence-based patient care.

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Building a bridge from the swamp to the ivory tower: Conducting randomised controlled trials in general practice

Cited by 3 publications

References 16 publications

Improving blood pressure control in primary care: The ImPress study

Improving blood pressure control in primary care: The ImPress study

Protocol for an open randomised controlled trial investigating Fibrin Glue in Skin grafts for Skin cancer (FiGSS)

General practice research priority setting in Australia: Informing a research agenda to deliver best patient care

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