Bullous erythema ab igne with cutaneous reactive angiomatosis

Hirohata, Ayaki; Hanafusa, Takaaki; Igawa, Ken; Inoue-Nishimoto, Tomoko; Mabuchi-Kiyohara, Eriko; Nakai, Chiaki; Kasugai, Tsutomu; Yokozeki, Hiroo; Ikegami, Ryoichi

doi:10.1684/ejd.2015.2690

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…Reactive angiomatosis occurring in EAI causing endothelial cell atypia has been reported within biopsy specimens of EAI in only 4 previous reports. 4,6–8 In the case presented here, although there was initial concern on histopathologic review for a malignant vascular neoplasm such as angiosarcoma, the discrepancy between the clinical description and histopathologic findings prompted the dermatopathologist to review the patient's history and clinical photographs in detail, for clinicopathologic correlation. Reactive angiomatosis, instead of a true vascular neoplasm, was then confirmed and supported by appropriate immunohistochemistry stains (positive CD31 and CD34).…”

Section: Answermentioning

confidence: 99%

Bullous Erythema ab Igne Unexpected Biopsy: Answer

Pincelli

Keeling

Sokumbi

2022

The American Journal of Dermatopathology

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Section: Answermentioning

confidence: 99%

Bullous Erythema ab Igne Unexpected Biopsy: Answer

Pincelli

Keeling

Sokumbi

2022

The American Journal of Dermatopathology

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“…Reactive angiomatosis—defined as a benign, reactive proliferation of atypical endothelial cells with enlarged, hyperchromatic nuclei and occasional mitotic figures lining vascular spaces—is a very rare finding within biopsy specimens of EAI, having been reported on only three previous occasions 3,5,6 . Prior to these reports, isolated atypia of endothelial cells without an associated vascular proliferation was known possibility 7 .…”

Section: Discussionmentioning

confidence: 99%

“…2,4 Reactive angiomatosis-defined as a benign, reactive proliferation of atypical endothelial cells with enlarged, hyperchromatic nuclei and occasional mitotic figures lining vascular spaces-is a very rare finding within biopsy specimens of EAI, having been reported on only three previous occasions. 3,5,6 Prior to these reports, isolated atypia of endothelial cells without an associated vascular proliferation was known possibility. 7 Reactive angiomatosis (reactive angioendotheliomatosis) is a poorly understood clinicopathologic entity that is thought to occur in response to vascular luminal obstruction by thrombotic material in the setting of numerous disease processes.…”

Section: Discussionmentioning

confidence: 99%

Rare mimic of angiosarcoma: Erythema ab igne with reactive angiomatosis

et al. 2021

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Erythema ab igne is an uncommon physical dermatosis that presents with localized patches of reticulated erythema and hyperpigmentation corresponding with the underlying dermal venous plexus. The rash occurs in response to chronic heat exposure that does not meet the threshold for thermal burn of the skin. The histopathologic findings are characterized by atrophy and thinning of the epidermis, focal hyperkeratosis, and keratinocyte atypia. The dermis displays dilated capillaries, evidence of pigment incontinence, and prominent elastotic material. We report a case of a 65‐year‐old male who presented to his primary care physician with a 1‐year history of reticular erythema and hyperpigmentation with focal ulceration on his right lateral leg. Histopathology on biopsy revealed mild hyperkeratosis and focal epidermal atrophy; however, the most striking finding was a proliferation of dermal vascular spaces lined by pleomorphic endothelial cells and numerous mitotic figures, which was morphologically compatible with angiosarcoma. However, clinicopathologic correlation and immunostaining revealed an actual diagnosis of erythema ab igne with reactive angiomatosis. Reactive angiomatosis—morphologically mimicking angiosarcoma—is a rarely reported feature of severe erythema ab igne, and dermatopathologists should be aware of this possibility to avoid misdiagnosis of erythema ab igne as angiosarcoma.

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Erythema Ab Igne Successfully Treated With Mesoglycan and Bioflavonoids: A Case-Report

Gianfaldoni¹,

Gianfaldoni²,

Tchernev³

et al. 2017

Open Access Maced J Med Sci

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Erythema ab igne is a localised, cutaneous condition consisting of reticulate hyperpigmentation, epidermal atrophy, and telangiectasias. It is caused by repetitive and prolonged exposure to moderate heat that is insufficient for producing burns. Currently, erythema ab igne is most commonly observed following repeated use of hot water bottles, infrared lamps and heating pads. If not properly treated, erythema ab igne can become chronic and even malignant. We report a case of erythema ab igne, successfully treated with systemic mesoglycan-based therapy, and local therapy with bioflavonoids.

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Bullous erythema ab igne with cutaneous reactive angiomatosis

Cited by 3 publications

References 6 publications

Bullous Erythema ab Igne Unexpected Biopsy: Answer

Bullous Erythema ab Igne Unexpected Biopsy: Answer

Rare mimic of angiosarcoma: Erythema ab igne with reactive angiomatosis

Erythema Ab Igne Successfully Treated With Mesoglycan and Bioflavonoids: A Case-Report

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