Bullous Pemphigoid

Patterson, James W.; Ali, Mapar Mohammad; Murray, John; Hazra, Tapan A.

doi:10.1111/j.1365-4362.1985.tb05751.x

Cited by 23 publications

(6 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, immunofluorescence study plays an important role to exclude a coexisting autoimmune disease. Moreover, several therapeutic modalities for MF have been shown to induce vesicles and blisters including topical mechlorethamine [ 4 ], interferon alfa [ 5 ], and phototherapy [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Large-Cell Transformed Mycosis Fungoides Coexisting with Mycosis Fungoides Bullosa: A Case Report and Review of the Literature

2017

View full text Add to dashboard Cite

Mycosis fungoides is the most common form of cutaneous T-cell lymphoma. Both large-cell transformed mycosis fungoides and mycosis fungoides bullosa are rare presentations and predict unfavorable prognosis. We report the case of a 61-year-old woman who presented with generalized erythematous scaly annular plaques, and histopathology confirmed the diagnosis of mycosis fungoides. She was treated with various conventional therapies but only achieved partial response and always relapsed after discontinuation of treatment. Her last treatment was combined chemotherapy (CHOP regimen) followed by romidepsin. However, 1 month after the last cycle of romidepsin, she developed multiple ulcerative masses and nodules. Skin biopsy was compatible with CD30⁺ large cell transformation, and she was treated with a new combination of chemotherapy (ifosfamide, carboplatin, etoposide). One day after receiving chemotherapy, multiple tense bullae on normal-appearing skin and mycosis fungoid plaques erupted. A histological study demonstrated subepidermal blistering with epidermotropism of atypical lymphocytes. Direct immunofluorescence study was negative. The results confirmed the diagnosis of mycosis fungoides bullosa. We present the first reported case of large-cell transformed mycosis fungoides coexisting with mycosis fungoides bullosa.

show abstract

Section: Discussionmentioning

confidence: 99%

Large-Cell Transformed Mycosis Fungoides Coexisting with Mycosis Fungoides Bullosa: A Case Report and Review of the Literature

2017

View full text Add to dashboard Cite

show abstract

“…An association with concomitant bullous pemphigoid or previous treatment with psoralen UVA photochemotherapy has been reported [5]. Bowman et al .…”

Section: Discussionmentioning

confidence: 99%

Mycosis fungoides bullosa: a case report and review of the literature

2010

View full text Add to dashboard Cite

IntroductionMycosis fungoides, the most common type of cutaneous T-cell lymphoma, can manifest in a variety of clinical and histological forms. Bulla formation is an uncommon finding in mycosis fungoides and only approximately 20 cases have been reported in the literature.Case presentationWe present a case of rapidly progressive mycosis fungoides in a 68-year-old Caucasian man who initially presented with erythematous plaques characterised by blister formation.ConclusionAlthough mycosis fungoides bullosa is extremely rare, it has to be regarded as an important clinical subtype of cutaneous T-cell lymphoma. Mycosis fungoides bullosa represents a particularly aggressive form of mycosis fungoides and is associated with a poor prognosis. The rapid disease progression in our patient confirms bulla formation as an adverse prognostic sign in cutaneous T-cell lymphoma.

show abstract

“…Blistering diseases are generally based on autoimmune mechanisms and this is also observed in relation with other diseases such as mycosis fungoides (MF). Two cases with MF are reported to have developed BP during treatment with PUVA, topical nitrogen mustard or UV-B [35]. The first was treated with methotrexate and prednisone for the BP and with a total body irradiation for MF.…”

Section: Discussionmentioning

confidence: 99%