Bullous Wells' Syndrome Associated with Non-Hodgkin's Lymphocytic Lymphoma

Spinelli, Matteo; Frigerio, E.; Cozzi, Alessandra; Garutti, C.; Garavaglia, Maria Lisa; Gf, Altomare

doi:10.2340/00015555-0492

Cited by 21 publications

(14 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although it may present a polymorphic clinical picture, recurrent pruritic, erythematous and edematous plaques are typical, affecting more frequently the trunk, face, arms and neck, that tend to regress with hyperpigmentation. 6 , 7 The lesions may be preceded by local pain and a burning sensation, associated with fever, malaise, arthralgia and liver function abnormalities, besides peripheral blood eosinophilia in up to 50% of cases. 2 , 5 , 7 …”

Section: Introductionmentioning

confidence: 99%

Wells syndrome associated with chronic lymphocytic leukemia

Stuhr

Vale

2015

An. Bras. Dermatol.

View full text Add to dashboard Cite

Eosinophilic cellulitis or Wells syndrome is an uncommon skin condition of unknown etiology that can occur alone or associated with other conditions. Typically, it presents with recurrent pruritic, erythematous and edematous plaques, but it can also show clinical polymorphism. Besides the cutaneous lesions, patients can experience systemic manifestations like fever, malaise, arthralgia and peripheral blood eosinophilia. We describe a case of this rare syndrome that presented with polymorphic cutaneous lesions associated with a serious systemic disease, which was revealed through the investigation of the cutaneous disease.

show abstract

Section: Introductionmentioning

confidence: 99%

Wells syndrome associated with chronic lymphocytic leukemia

Stuhr

Vale

2015

An. Bras. Dermatol.

View full text Add to dashboard Cite

show abstract

“…Wells syndrome is considered as a hypersensitivity reaction in response to various exogenous and endogenous stimuli. Thus, it has been described in association with arthropod bites, medications, viral, parasitic, fungal, bacterial infections, malignancies, and vaccinations [24,[30][31][32][33][34][35]. Although all parasitic serology tests were not performed in our patient but the neonatal onset of the disease and the negativity of the repeated infectious investigations in a child in exclusive maternal diet eliminate an infectious origin.…”

Section: Discussionmentioning

confidence: 70%

Neonatal Wells Syndrome Associated With Eosinophilic Gastroenteritis

2017

JCRC

View full text Add to dashboard Cite

Background: Eosinophilic cellulitis (Wells syndrome) is an uncommon eosinophilic dermatosis of unknown pathogenesis, which signals undiagnosed infectious, malignant or systemic disease. It has been reported exceptionally in association with inflammatory bowel disease. Case report: A 7-month-old female infant, whose parents had no particular medical history, was seen for pruriginouspapulo-nodular lesions evolving since her birth. She was followed for evolutive intestinal pseudoobstruction, diagnosed as Hirschsprung disease, and was treated by discharge colostomy after an obstruction. Biological examinations showed hypereosinophilia and anaemia. Skin hispathology revealed a dense eosinophilic infiltrate, with flame figures typical of eosinophilic cellulitis. Histopathology of the resected colon showed a dense eosinophilic infiltrate throughout the bowel wall, with the presence of ganglion cells and normal nervous plexus. Discussion: This case of eosinophilic cellulitis is of particular interest because of its neonatal occurrence, nodular presentation and association with eosinophilic gastroenteritis. To our knowledge, this is the third reported association between eosinophilic cellulitis and eosinophilic gastroenteritis, which appear to have the same pathophysiology. Wells syndrome should therefore be added to the list of dermatosis associated with inflammatory bowel disease.

show abstract

“…Occasionally bullous, granulomatous papular and nodular eruptions may be seen. Lower limbs are frequently involved and typically present with cellulitis-like eruptions [10][11] .…”

Section: Discussionmentioning

confidence: 99%

Eosinophilic Cellulitis (Wells Syndrome)

Almutlaga¹

2016

BMB

View full text Add to dashboard Cite

Bullous Wells' Syndrome Associated with Non-Hodgkin's Lymphocytic Lymphoma

Cited by 21 publications

References 14 publications

Wells syndrome associated with chronic lymphocytic leukemia

Wells syndrome associated with chronic lymphocytic leukemia

Neonatal Wells Syndrome Associated With Eosinophilic Gastroenteritis

Eosinophilic Cellulitis (Wells Syndrome)

Contact Info

Product

Resources

About